Although our ability to store semantic declarative information can nowadays be readily
surpassed by that of simple personal computers, our ability to learn and express procedural …

The cerebellum represents a brain compartment that first appeared in gnathostomes (jawed
vertebrates). Besides the addition of cell numbers, its development, cytoarchitecture …

Revealing the organization and function of neural circuits is greatly facilitated by viral tools
that spread transsynaptically. Adeno-associated virus (AAV) exhibits anterograde …

Due to the uniform cyto-architecture of the cerebellar cortex, its overall physiological
characteristics have traditionally been considered to be homogeneous. In this study, we …

Three decades of electrophysiological research on cerebellar cortical activity underlying
Pavlovian conditioning have expanded our understanding of motor learning in the brain …

Theories of cerebellar function place the inferior olive to cerebellum connection at the centre
of motor behaviour. One possible implication of this is that disruption of olivocerebellar …

The optogenetic tool channelrhodopsin-2 (ChR2) is widely used to excite neurons to study
neural circuits. Previous optogenetic studies of synapses suggest that light-evoked synaptic …

Purkinje cell dendrites convert excitatory climbing fiber input into signals that instruct
plasticity and motor learning. Modulation of instructive signaling may increase the range in …

The cerebellum refines the accuracy and timing of motor performance. How it encodes
information to perform these functions is a major topic of interest. We performed whole cell …

To understand how the cerebellar cortex transforms mossy fiber (MF) inputs into Purkinje
cell (PC) outputs, it is vital to delineate the elements of this circuit. Candelabrum cells (CCs) …