Abstract Coronavirus disease 2019 (Covid-19) is a worldwide infectious disease caused by
severe acute respiratory coronavirus 2 (SARS-CoV-2). In severe SARS-CoV-2 infection …

Thrombomodulin (TM), which is predominantly expressed on the endothelium, plays an
important role in maintaining vascular homeostasis by regulating the coagulation system …

Neutrophil extracellular traps (NETs) are large DNA reticular structures secreted by
neutrophils and decorated with histones and antimicrobial proteins. As a key mechanism for …

Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a common disease with
high morbidity and mortality, and its pathogenesis is believed to be related to oxidative …

Acute kidney injury (AKI) occurs in about half of critically ill patients and is associated with
high in-hospital mortality, increased long-term mortality postdischarge, and subsequent …

Complement C3 plays a prominent role in inflammatory processes, and its increase
exacerbates ischemia reperfusion injury (IRI)-induced acute kidney injury (AKI). Infiltrated …

Neutrophil extracellular trap (NETosis), the web-like structures induced by neutrophil death,
is an important inflammatory mechanism of the immune system leading to reactive oxygen …

Many gut disease etiologies are attributed to the presence of robust inflammatory cell
recruitment. The recruitment of neutrophils plays a vital role in inflammatory infiltration …

Ischemia reperfusion (IR) can lead to acute kidney injury and can be complicated by acute
lung injury, which is one of the leading causes of acute kidney injury‐related death. Peptidyl …

In response to strong signals, several types of immune cells release extracellular traps
(ETs), which are web-like structures consisting of DNA decorated with various protein …