The balance between immune effector cells and immunosuppressive cells and how this
regulates the tumor microenvironment has been well described. A significant contribution of …

B Lymphocytes and Cancer: A Love–Hate Relationship: Trends in Cancer Skip to Main Content
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Abstract Background Regulatory B (Breg) cells represent one of the B cell subsets that
infiltrate solid tumors and exhibit distinct phenotypes in different tumor microenvironments …

B cells play a central role in the immune system through the production of antibodies. During
the past two decades, it has become increasingly clear that B cells also have the capacity to …

B cells often constitute abundant cellular components in human tumors. Regulatory B cells
that are functionally defined by their ability to produce IL10 downregulate inflammation and …

The balance between immune effector cells such as T cells and natural killer cells, and
immunosuppressive Treg cells, dendritic, myeloid and monocytic sub-populations in the …

Accumulating evidence has indicated that immune regulatory cells are involved in the
establishment of tumoral immune evasion. However, the role of regulatory B cells (Bregs) in …

Objectives Increase of regulatory T cells (Tregs) in the tumor microenvironment predicts
worse survival of patients with various types of cancer including tongue squamous cell …

Advances in understanding of the immune microenvironment have highlighted the role of
immunosuppressive T cell, myeloid, dendritic and monocytic sub-populations in inhibition of …

Recent researches shed light on B cell role on various autoimmune diseases, including
autoantibody-mediated diseases as well as T cell-mediated autoimmune diseases such as …