The zebrafish (Danio rerio) is now the pre-eminent vertebrate model system for clarification
of the roles of specific genes and signaling pathways in development. The zebrafish …

Genetically encoded calcium indicators (GECIs), which are based on chimeric fluorescent
proteins, can be used to monitor calcium transients in living cells and organisms. Because …

Genetically encoded calcium indicators (GECIs) can be used to image activity in defined
neuronal populations. However, current GECIs produce inferior signals compared to …

Larval zebrafish (Brachydanio rerio) are a popular model system because of their genetic
attributes, transparency and relative simplicity. They have approximately 200 neurons that …

Segmentation of the vertebrate brain is most obvious in the hindbrain, where successive
segments contain repeated neuronal types. One such set of three repeated reticulospinal …

Genetically encoded calcium indicators, such as cameleon, have offered the promise of
noninvasively monitoring activity of neurons, but no one has demonstrated whether these …

The visual pathway from the retina to the optic tectum in fish and frogs has long been studied
as a model for neural circuit formation. Although morphological aspects, such as axonal and …

The ability of an animal to carry out its normal behavioral repertoire requires generation of
an enormous diversity of neurons and glia. The relative simplicity of the spinal cord makes …

The field of neurotoxicology needs to satisfy two opposing demands: the testing of a growing
list of chemicals, and resource limitations and ethical concerns associated with testing using …

Swimming and turning behaviors of larval zebrafish have been described kinematically, but
prey capture behaviors are less well characterized. High-speed digital imaging was used to …