The synthetic and therapeutic expedition of isoxazole and its analogs
Isoxazole, constituting an important family of five-membered heterocycles with one oxygen
atom and one nitrogen atom at adjacent positions is of immense importance because of its …
atom and one nitrogen atom at adjacent positions is of immense importance because of its …
Recent progress in the synthesis of isoxazoles
DX Duc, VC Dung - Current Organic Chemistry, 2021 - ingentaconnect.com
Isoxazole derivatives are aromatic five-membered ring heterocyclic compounds with one
oxygen atom and one nitrogen atom at adjacent positions. These compounds have a broad …
oxygen atom and one nitrogen atom at adjacent positions. These compounds have a broad …
Preparation of 3, 5-disubstituted pyrazoles and isoxazoles from terminal alkynes, aldehydes, hydrazines, and hydroxylamine
R Harigae, K Moriyama, H Togo - The Journal of organic …, 2014 - ACS Publications
The reaction of terminal alkynes with n-BuLi, and then with aldehydes, followed by the
treatment with molecular iodine, and subsequently hydrazines or hydroxylamine provided …
treatment with molecular iodine, and subsequently hydrazines or hydroxylamine provided …
Multicomponent reactions: a sustainable tool to 1, 2-and 1, 3-azoles
KN Singh - Organic & Biomolecular Chemistry, 2018 - pubs.rsc.org
Multicomponent reactions (MCRs) have emerged as an efficient and eco-safe approach in
organic synthesis. The influential nature of this approach has been well established in the …
organic synthesis. The influential nature of this approach has been well established in the …
A study on synthesis of chalcone derived-5-membered isoxazoline and isoxazole scaffolds
Chalcone-derived isoxazole scaffolds remain the central focus due to their greater
biological, clinical, and pharmacological properties. The present study reviews the synthesis …
biological, clinical, and pharmacological properties. The present study reviews the synthesis …
Visible-Light-Mediated Synthesis of 1, 2, 4-Dithiazolidines from β-Ketothioamides through a Hydrogen-Atom-Transfer Photocatalytic Approach of Eosin Y
An efficient protocol for visible-light-mediated synthesis of a specific class of 1, 2, 4-
dithiazolidines from β-ketothioamides is devised employing eosin Y as a photoinitiator at …
dithiazolidines from β-ketothioamides is devised employing eosin Y as a photoinitiator at …
Metal-and Catalyst-Free, Formal [4+ 1] Annulation via Tandem C O/C S Functionalization: One-Pot Access to 3, 5-Disubstituted/Annulated Isothiazoles
An operationally simple and user-friendly new protocol for the synthesis of 3, 5-disubstituted/
annulated isothiazoles is devised utilizing β-ketodithioesters/β-ketothioamides and NH4OAc …
annulated isothiazoles is devised utilizing β-ketodithioesters/β-ketothioamides and NH4OAc …
Facile, capable, atom-economical one-pot multicomponent strategy for the direct regioselective synthesis of novel isoxazolo[5,4-d]pyrimidines
Facile and efficient NaOH-promoted one-pot regioselective synthesis of 5, 7-dimethyl-3-
(arylamino) isoxazolo [5, 4-d] pyrimidine-4, 6 (5 H, 7 H)-diones and 5, 7-dimethyl-3 …
(arylamino) isoxazolo [5, 4-d] pyrimidine-4, 6 (5 H, 7 H)-diones and 5, 7-dimethyl-3 …
Synthetic applications and computational perspectives on eosin Y induced direct HAT process
J Inoa, G Dominici, R Eldabagh, JJ Foley IV, Y Xing - Synthesis, 2021 - thieme-connect.com
In recent years, advancements in photocatalysis have allowed for a plethora of chemical
transformations under milder conditions. Many of these photochemical reactions utilize …
transformations under milder conditions. Many of these photochemical reactions utilize …
General Platform for the Conversion of Isoxazol‐5‐ones to 3, 5‐Disubstituted Isoxazoles via Nucleophilic Substitutions and Palladium Catalyzed Cross‐Coupling …
AAG Fernandes, AF da Silva… - European Journal of …, 2019 - Wiley Online Library
A general platform for the conversion of isoxazol‐5‐ones to 3, 5‐disubstituted isoxazoles
has been developed via a two‐step strategy. The first step leads to the formation of 5 …
has been developed via a two‐step strategy. The first step leads to the formation of 5 …