Insulin-like growth factor-1 (IGF-1) is a key growth factor that regulates both anabolic and
catabolic pathways in skeletal muscle. IGF-1 increases skeletal muscle protein synthesis via …

Assessing respiratory mechanics and muscle function is critical for both clinical practice and
research purposes. Several methodological developments over the past two decades have …

Background Patients with coronavirus disease 2019 (COVID-19) or post-COVID-19 will
probably have a need for rehabilitation during and directly after the hospitalisation. Data on …

Background Coronavirus disease 2019 (COVID-19) can result in a large variety of chronic
health issues such as impaired lung function, reduced exercise performance and diminished …

Rationale: Pulmonary rehabilitation (PR) has demonstrated physiological, symptom-
reducing, psychosocial, and health economic benefits for patients with chronic respiratory …

Dyspnea is the most common symptom experienced by patients with chronic obstructive
pulmonary disease (COPD). To avoid exertional dyspnea, many patients adopt a sedentary …

Skeletal muscle dysfunction occurs in patients with chronic obstructive pulmonary disease
(COPD) and affects both ventilatory and nonventilatory muscle groups. It represents a very …

Importance There are 30 million adults (12%) in the United States who have chronic
obstructive pulmonary disease (COPD). Chronic obstructive pulmonary disease accounts for …

Background Age-related loss of muscle, sarcopenia, is recognised as a clinical syndrome
with multiple contributing factors. International European Working Group on Sarcopenia in …

Sarcopenia and frailty are geriatric syndromes characterized by multisystem decline, which
are related to and reflected by markers of skeletal muscle dysfunction. In older people …