Antibiotics-free nanomaterials against bacterial keratitis: Eliminating infections with reactive oxygen species (ROS)
L Zhou, Y Deng, Y Ren, HL Poon, WY Chu… - Chemical Engineering …, 2024 - Elsevier
Bacterial keratitis (BK), which accounts for over 50% of the reported cases of microbial
keratitis, is a condition that can result in vision loss and blindness if left untreated. Antibiotics …
keratitis, is a condition that can result in vision loss and blindness if left untreated. Antibiotics …
[HTML][HTML] Emerging antimicrobial resistance and need for antimicrobial stewardship for ocular infections in India: A narrative review
P Biswas, S Batra, N Gurha… - Indian Journal of …, 2022 - journals.lww.com
Patients with ocular infections are at increased risk of vision impairment and may require
immediate medical care to preserve their vision. Management of ocular bacterial infections …
immediate medical care to preserve their vision. Management of ocular bacterial infections …
Chitosan-poly (lactide-co-glycolide)/poloxamer mixed micelles as a mucoadhesive thermo-responsive moxifloxacin eye drop to improve treatment efficacy in bacterial …
A mucoadhesive self-assembling polymeric system was developed to carry moxifloxacin (M)
for treating bacterial keratitis (BK). Chitosan-PLGA (C) conjugate was synthesized, and …
for treating bacterial keratitis (BK). Chitosan-PLGA (C) conjugate was synthesized, and …
Simultaneous determination of amphotericin B, tobramycin and vancomycin in rabbit ocular biofluids and tissues by LC-MS/MS: An antimicrobial therapy for keratitis …
A Mishra, A Biswas, AD Choudhury, S Verma… - … of Chromatography B, 2024 - Elsevier
A rationale poly-microbial keratitis (PMK) therapy requires quick identification of pathogen
(bacteria and fungi) and their efficient treatment. However, majority of healthcare providers …
(bacteria and fungi) and their efficient treatment. However, majority of healthcare providers …
Ciprofloxacin resistance and tolerance of Pseudomonas aeruginosa ocular isolates
M Khan, K Ma, I Wan, MDP Willcox - Contact Lens and Anterior Eye, 2023 - Elsevier
Purpose Tolerance to antibiotics may occur due to changes in bacterial growth patterns and
can be a precursor to development of resistance. However, there is a lack of information on …
can be a precursor to development of resistance. However, there is a lack of information on …
Vision redemption: Self-reporting AIEgens for combined treatment of bacterial keratitis
C Peng, W Sun, C Zhou, S Qiang, M Jiang, JWY Lam… - Biomaterials, 2021 - Elsevier
Bacterial keratitis (BK) is one of the most commonly leading causes of visual impairment and
blindness worldwide, and suffers the risk of drug-resistant infections due to the abuse of …
blindness worldwide, and suffers the risk of drug-resistant infections due to the abuse of …
Preparation and characterization of amphotericin B-loaded silk fibroin nanoparticles-in situ hydrogel composites for topical ophthalmic application
P Chomchalao, N Saelim, W Tiyaboonchai - Journal of Materials Science, 2022 - Springer
The objective of this study was to develop and characterize a novel combined systems of
amphotericin B-loaded silk fibroin nanoparticles (AmB-FNPs) and in situ hydrogel for ocular …
amphotericin B-loaded silk fibroin nanoparticles (AmB-FNPs) and in situ hydrogel for ocular …
[HTML][HTML] Genipin in an ex vivo corneal model of bacterial and fungal keratitis
E Koudouna, M Huertas-Bello… - … Vision Science & …, 2021 - iovs.arvojournals.org
Purpose: To determine whether genipin (a natural crosslinker) could reduce the colonization
and proliferation of bacteria and fungi in an ex vivo model of corneal infection. Methods: This …
and proliferation of bacteria and fungi in an ex vivo model of corneal infection. Methods: This …
Delay along the care seeking journey of patients with microbial keratitis in Uganda
Purpose To describe the care seeking journey and causes of delay among patients with
Microbial Keratitis in Uganda. Methods A prospective cohort of patients presenting with …
Microbial Keratitis in Uganda. Methods A prospective cohort of patients presenting with …
Poly‐ε‐Lysine or Mel4 Antimicrobial Surface Modification on a Novel Peptide Hydrogel Bandage Contact Lens
R Lace, KG Doherty, D Dutta… - Advanced Materials …, 2020 - Wiley Online Library
Microbial keratitis (MK) is a serious issue in many countries and is often caused by contact
lens wear. Antimicrobial peptides (AMPs) are a potentially useful tool for creating …
lens wear. Antimicrobial peptides (AMPs) are a potentially useful tool for creating …