One of the most common monogenic forms of Parkinson disease (PD) is caused by
mutations in the LRRK2 gene that encodes leucine-rich repeat kinase 2 (LRRK2). LRRK2 …

Parkinson's disease is a neurological disorder with evolving layers of complexity. It has long
been characterised by the classical motor features of parkinsonism associated with Lewy …

Genes | Free Full-Text | Monogenic Parkinson’s Disease: Genotype, Phenotype,
Pathophysiology, and Genetic Testing Next Article in Journal enChIP-Seq Analyzer: A …

Inflammatory bowel disease and Parkinson's disease are chronic progressive disorders that
mainly affect different organs: the gut and brain, respectively. Accumulating evidence has …

Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants,
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …

Parkinson's disease is a common, progressive neurodegenerative disorder, affecting 3% of
those older than 75 years of age. Clinically, Parkinson's disease (PD) is associated with …

Fifteen years of genetic research in Parkinson's disease (PD) have led to the identification of
several monogenic forms of the disorder and of numerous genetic risk factors increasing the …

The etiology of Parkinson's disease (PD) is not well understood but likely to involve both
genetic and environmental factors. Incidence and prevalence estimates vary to a large …

The common fruit fly, Drosophila melanogaster, is a well studied and highly tractable genetic
model organism for understanding molecular mechanisms of human diseases. Many basic …

Over the last two decades, we have witnessed a revolution in the field of Parkinson's
disease (PD) genetics. Great advances have been made in identifying many loci that confer …