Sickle cell syndromes, including sickle cell disease (SCD) and sickle cell trait, are
associated with multiple kidney abnormalities. Young patients with SCD have elevated …

Background: Sickle cell disease is an inherited red blood cell disorder that affects
approximately 100,000 people in the USA and 25 million people worldwide. Vaso-occlusion …

The increasing number of patients undergoing dialysis due to diabetes mellitus (DM) is
causing serious economic problems, and its reduction is an urgent policy issue in developed …

Glomerular hyperfiltration is common in young sickle cell anemia patients and precedes
development of overt kidney disease. In this multicenter pooled cohort, we characterized …

End-organ dysfunction results in substantial morbidity and mortality in sickle cell disease
(SCD). 1-3 Chronic kidney disease (CKD), defined as kidney damage or decreased kidney …

Patients with sickle cell disease (SCD) experience increased morbidity and early mortality,
due in part to organ damage, including end stage kidney disease (ESKD) 1. Decline in …

Purpose This study aimed to explore the correlation between hemoglobin levels and
albuminuria in US adults. Methods This cross-sectional investigation analyzed the National …

Glomerular hyperfiltration is common in sickle cell disease (SCD) and precedes proteinuria
and declining kidney function. We evaluated hyperfiltration in SCD patients and its …

The primary treatment goal of chronic kidney disease (CKD) is preserving renal function and
preventing its progression to end-stage renal disease. Glomerular hypertension and tubular …

Sickle cell disease (SCD) is the most common monogenic disorder in Saudi Arabia, which
associates with an increased risk of organs damage, including the kidney. The aim of this …