Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most formidable challenge to …

Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

Viral variants of concern may emerge with dangerous resistance to the immunity generated
by the current vaccines to prevent coronavirus disease 2019 (Covid-19). Moreover, if some …

The COVID-19 outbreak has demonstrated the diverse challenges that supply chains face to
significant disruptions. Vaccine supply chains are no exception. Therefore, it is elemental …

Remdesivir (GS-5734) is a 1′-cyano-substituted adenosine nucleotide analogue prodrug
that shows broad-spectrum antiviral activity against several RNA viruses. This compound is …

Ever since the development of the first vaccine more than 200 years ago, vaccinations have
greatly decreased the burden of infectious diseases worldwide, famously leading to the …

Fifty years since the first description of an association between HLA and human disease,
HLA molecules have proven to be central to physiology, protective immunity and …

Implementation research is important in global health because it addresses the challenges
of the know–do gap in real-world settings and the practicalities of achieving national and …

Viral vectors have been used for a broad spectrum of gene therapy for both acute and
chronic diseases. In the context of cancer gene therapy, viral vectors expressing anti-tumor …

The recent Ebola virus (EBOV) outbreak in West Africa was the largest recorded in history
with over 28,000 cases, resulting in> 11,000 deaths including> 500 healthcare workers. A …