In recent years, there has been a major paradigm shift in the management of non-small cell
lung cancer (NSCLC). NSCLC should now be further sub-classified by histology and driver …

Emerging evidence on the role of the antitumor activity of the immune system has generated
great interest in immunotherapy even for tumors that were historically considered as …

Purpose: Tumors are continuously evolving biological systems, and medical imaging is
uniquely positioned to monitor changes throughout treatment. Although qualitatively tracking …

Introduction Our aim was to update global lung cancer epidemiology and describe changing
trends and disparities. Methods We presented country-specific incidence and mortality from …

Summary Background The phase 3 LUME-Lung 1 study assessed the efficacy and safety of
docetaxel plus nintedanib as second-line therapy for non-small-cell lung cancer (NSCLC) …

ABSTRACT KRAS mutations in non-small-cell lung cancer (NSCLC) are associated with
poor prognosis. Trametinib, a selective inhibitor of MEK1/MEK2, demonstrated similar …

Lung cancer is an umbrella term for a subset of heterogeneous diseases that are collectively
responsible for the most cancer-related deaths worldwide. Despite the tremendous progress …

Background Lung cancer is the most common cause of cancer-related mortality in humans.
There are several reasons for this high rate of mortality, including metastasis to several …

Abstract Objectives The MYLUNG (Molecularly Informed Lung Cancer Treatment in a
Community Cancer Network) consortium pragmatic study assessed real-world biomarker …

Background This study was conducted to determine how malignant pleural mesothelioma
(MPM) histology was associated with the use of surgery and survival. Methods Overall …