Mitochondrial signal transduction
M Picard, OS Shirihai - Cell Metabolism, 2022 - cell.com
The analogy of mitochondria as powerhouses has expired. Mitochondria are living, dynamic,
maternally inherited, energy-transforming, biosynthetic, and signaling organelles that …
maternally inherited, energy-transforming, biosynthetic, and signaling organelles that …
Angiotensin II signal transduction: an update on mechanisms of physiology and pathophysiology
The renin-angiotensin-aldosterone system plays crucial roles in cardiovascular physiology
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …
and pathophysiology. However, many of the signaling mechanisms have been unclear. The …
Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release
G protein-coupled receptors (GPCRs) are classically characterized as cell-surface receptors
transmitting extracellular signals into cells. Here we show that central components of a …
transmitting extracellular signals into cells. Here we show that central components of a …
G protein–coupled receptor signaling: new insights define cellular nanodomains
G protein–coupled receptors are the largest and pharmacologically most important receptor
family and are involved in the regulation of most cell functions. Most of them reside …
family and are involved in the regulation of most cell functions. Most of them reside …
Sarcopenia in older adults
JD Walston - Current opinion in rheumatology, 2012 - journals.lww.com
Efforts to develop a consensus definition are ongoing and will greatly facilitate the
development and testing of novel interventions for sarcopenia. Although pharmaceutical …
development and testing of novel interventions for sarcopenia. Although pharmaceutical …
Implications of oxidative stress and potential role of mitochondrial dysfunction in COVID-19: therapeutic effects of vitamin D
N de Las Heras, VM Martín Giménez, L Ferder… - Antioxidants, 2020 - mdpi.com
Due to its high degree of contagiousness and like almost no other virus, SARS-CoV-2 has
put the health of the world population on alert. COVID-19 can provoke an acute inflammatory …
put the health of the world population on alert. COVID-19 can provoke an acute inflammatory …
Brain renin–angiotensin system at the intersect of physical and cognitive frailty
C Cosarderelioglu, LS Nidadavolu… - Frontiers in …, 2020 - frontiersin.org
The renin–angiotensin system (RAS) was initially considered to be part of the endocrine
system regulating water and electrolyte balance, systemic vascular resistance, blood …
system regulating water and electrolyte balance, systemic vascular resistance, blood …
Psychological stress and mitochondria: a conceptual framework
M Picard, BS McEwen - Psychosomatic medicine, 2018 - journals.lww.com
Background The integration of biological, psychological, and social factors in medicine has
benefited from increasingly precise stress response biomarkers. Mitochondria, a subcellular …
benefited from increasingly precise stress response biomarkers. Mitochondria, a subcellular …
Biochemical evaluation of the renin-angiotensin system: the good, bad, and absolute?
MC Chappell - American Journal of Physiology-Heart and …, 2016 - journals.physiology.org
The renin-angiotensin system (RAS) constitutes a key hormonal system in the physiological
regulation of blood pressure through peripheral and central mechanisms. Indeed …
regulation of blood pressure through peripheral and central mechanisms. Indeed …
[HTML][HTML] The renin angiotensin system, oxidative stress and mitochondrial function in obesity and insulin resistance
Obesity is a complex disease characterized by excessive expansion of adipose tissue and is
an important risk factor for chronic diseases such as cardiovascular disorders, hypertension …
an important risk factor for chronic diseases such as cardiovascular disorders, hypertension …