NIH working group report: innovative research to improve maintenance of weight loss

PS MacLean, RR Wing, T Davidson, L Epstein… - …, 2015 - Wiley Online Library
Objectives The National Institutes of Health, led by the National Heart, Lung, and Blood
Institute, organized a working group of experts to discuss the problem of weight regain after …

Long-term adherence to health behavior change

KR Middleton, SD Anton… - American journal of …, 2013 - journals.sagepub.com
The utility of lifestyle-based health promotion interventions is directly affected by participant
adherence to prescribed behavior changes. Unfortunately, poor adherence to behaviors …

中国超重和肥胖造成相关慢性疾病的经济负担研究

赵文华, 翟屹, 胡建平, 王建生, 杨正雄, 孔灵芝… - 中华流行病学 …, 2006 - chinaepi.icdc.cn
目的评价由超重和肥胖造成的4 种慢性疾病(高血压, 糖尿病, 冠心病, 脑卒中) 的直接经济负担,
预测不同超重和肥胖率比值下的医疗负担变化. 方法利用2002 年中国居民营养与健康状况调查 …

Central nervous system regulation of organismal energy and glucose homeostasis

MG Myers Jr, AH Affinati, N Richardson… - Nature …, 2021 - nature.com
Growing evidence implicates the brain in the regulation of both immediate fuel availability
(for example, circulating glucose) and long-term energy stores (that is, adipose tissue mass) …

Biology's response to dieting: the impetus for weight regain

PS MacLean, A Bergouignan… - American Journal …, 2011 - journals.physiology.org
Dieting is the most common approach to losing weight for the majority of obese and
overweight individuals. Restricting intake leads to weight loss in the short term, but, by itself …

The role for adipose tissue in weight regain after weight loss

PS MacLean, JA Higgins, ED Giles, VD Sherk… - Obesity …, 2015 - Wiley Online Library
Weight regain after weight loss is a substantial challenge in obesity therapeutics. Dieting
leads to significant adaptations in the homeostatic system that controls body weight, which …

Metabolic adaptation to weight loss: implications for the athlete

ET Trexler, AE Smith-Ryan, LE Norton - Journal of the international society …, 2014 - Springer
Optimized body composition provides a competitive advantage in a variety of sports. Weight
reduction is common among athletes aiming to improve their strength-to-mass ratio …

Understanding and addressing the epidemic of obesity: an energy balance perspective

JO Hill - Endocrine reviews, 2006 - academic.oup.com
The intent of this paper is to address the obesity epidemic, which is a term used to describe
the sudden and rapid increase in obesity rates that began in the 1980s and continues …

Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli

M Rosenbaum, M Sy, K Pavlovich… - The Journal of …, 2008 - Am Soc Clin Investig
Increased hunger and food intake during attempts to maintain weight loss are a critical
problem in clinical management of obesity. To determine whether reduced body weight …

Biological control of appetite: a daunting complexity

PS MacLean, JE Blundell, JA Mennella… - Obesity, 2017 - Wiley Online Library
Objective This review summarizes a portion of the discussions of an NIH Workshop
(Bethesda, MD, 2015) titled “Self‐Regulation of Appetite—It's Complicated,” which focused …