The neurobiological mechanisms by which childhood maltreatment heightens vulnerability
to psychopathology remain poorly understood. It is likely that a complex interaction between …

The stress response system is comprised of an intricate interconnected network that
includes the hypothalamic–pituitary–adrenocortical (HPA) axis. The HPA axis maintains the …

Major depressive disorder represents a serious public health challenge worldwide;
however, the underlying cellular and molecular mechanisms are mostly unknown. Here, we …

OBJECTIVE:: To review empirical findings on oppositional defiant disorder (ODD) and
conduct disorder (CD). METHOD:: Selected summaries of the literature over the past decade …

A meta-analysis of 95 studies was conducted to investigate the relations of heart rate (HR)
and electrodermal activity (EDA) with aggression, psychopathy, and conduct problems …

This chapter describes the current state of knowledge regarding the developmental
neurobiology of stress, its relation to psychiatric disorders, and the impact of early adverse …

OBJECTIVE: To assess whether antisocial children are characterized by low heart rate.
METHOD: A meta-analysis was conducted on 45 independent effect sizes of the resting …

BACKGROUND: Evidence from animal and human studies suggests that early-life stress
such as physical maltreatment has long-lasting effects on the hypothalamic-pituitary-adrenal …

Background: This article selectively reviews the biological bases of antisocial and
aggressive behavior in children with a focus on low autonomic functioning, prefrontal …

Children with persistent antisocial and aggressive behavior are diagnosed as having
disruptive behavior disorder. The authors review evidence that antisocial children, and …