Cognitive impairment in multiple sclerosis: clinical management, MRI, and therapeutic avenues
RHB Benedict, MP Amato, J DeLuca… - The Lancet …, 2020 - thelancet.com
Multiple sclerosis is a chronic, demyelinating disease of the CNS. Cognitive impairment is a
sometimes neglected, yet common, sign and symptom with a profound effect on instrumental …
sometimes neglected, yet common, sign and symptom with a profound effect on instrumental …
Cognition in multiple sclerosis: State of the field and priorities for the future
JF Sumowski, R Benedict, C Enzinger, M Filippi… - Neurology, 2018 - AAN Enterprises
Cognitive decline is recognized as a prevalent and debilitating symptom of multiple sclerosis
(MS), especially deficits in episodic memory and processing speed. The field aims to (1) …
(MS), especially deficits in episodic memory and processing speed. The field aims to (1) …
Recommendations for cognitive screening and management in multiple sclerosis care
R Kalb, M Beier, RHB Benedict… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Purpose: To promote understanding of cognitive impairment in multiple sclerosis (MS),
recommend optimal screening, monitoring, and treatment strategies, and address barriers to …
recommend optimal screening, monitoring, and treatment strategies, and address barriers to …
Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis
RHB Benedict, J DeLuca, G Phillips… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Cognitive and motor performance measures are commonly employed in multiple sclerosis
(MS) research, particularly when the purpose is to determine the efficacy of treatment. The …
(MS) research, particularly when the purpose is to determine the efficacy of treatment. The …
Treatment and management of cognitive dysfunction in patients with multiple sclerosis
J DeLuca, ND Chiaravalloti, BM Sandroff - Nature Reviews Neurology, 2020 - nature.com
Cognitive impairment is a common and devastating manifestation of multiple sclerosis (MS).
Although disease-modifying therapies have been efficacious for reducing relapse rates in …
Although disease-modifying therapies have been efficacious for reducing relapse rates in …
Clinical and imaging assessment of cognitive dysfunction in multiple sclerosis
MA Rocca, MP Amato, N De Stefano… - The Lancet …, 2015 - thelancet.com
In patients with multiple sclerosis (MS), grey matter damage is widespread and might
underlie many of the clinical symptoms, especially cognitive impairment. This relation …
underlie many of the clinical symptoms, especially cognitive impairment. This relation …
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype
B Hou, Y Zhang, P Liang, Y He, B Peng, W Liu… - Cell Death & …, 2020 - nature.com
Multiple sclerosis (MS) is a chronic disease that is characterized by demyelination and
axonal damage in the central nervous system. Cognitive deficits are recognized as one of …
axonal damage in the central nervous system. Cognitive deficits are recognized as one of …
The link between multiple sclerosis and depression
A Feinstein, S Magalhaes, JF Richard, B Audet… - Nature Reviews …, 2014 - nature.com
Depression—be it a formal diagnosis based on consensus clinical criteria, or a collection of
symptoms revealed by a self-report rating scale—is common in patients with multiple …
symptoms revealed by a self-report rating scale—is common in patients with multiple …
Recommendations for a brief international cognitive assessment for multiple sclerosis (BICAMS)
DW Langdon, MP Amato, J Boringa… - Multiple Sclerosis …, 2012 - journals.sagepub.com
Background: Cognitive impairment in MS impacts negatively on many patients at all disease
stages and in all subtypes. Full clinical cognitive assessment is expensive, requiring expert …
stages and in all subtypes. Full clinical cognitive assessment is expensive, requiring expert …
Predicting cognitive decline in multiple sclerosis: a 5-year follow-up study
AJC Eijlers, Q van Geest, I Dekker, MD Steenwijk… - Brain, 2018 - academic.oup.com
Cognitive decline is common in multiple sclerosis and strongly affects overall quality of life.
Despite the identification of cross-sectional MRI correlates of cognitive impairment …
Despite the identification of cross-sectional MRI correlates of cognitive impairment …