Sex and gender bias as a mechanistic determinant of cardiovascular disease outcomes

I Kim, TS Field, D Wan, K Humphries… - Canadian Journal of …, 2022 - Elsevier
Defined as a prejudice either for or against something, biases at the provider, patient, and
societal level all contribute to differences in cardiovascular disease recognition and …

Representation of women in stroke clinical trials: a review of 281 trials involving more than 500,000 participants

C Carcel, K Harris, SAE Peters, EC Sandset, G Balicki… - Neurology, 2021 - AAN Enterprises
Background and Objectives Women have been underrepresented in cardiovascular disease
clinical trials but there is less certainty over the level of disparity specifically in stroke. We …

Twenty-year change in severity and outcome of ischemic and hemorrhagic strokes

K Toyoda, S Yoshimura, M Nakai, M Koga… - JAMA …, 2022 - jamanetwork.com
Importance Whether recent changes in demographic characteristics and therapeutic
technologies have altered stroke outcomes remains unknown. Objective To determine …

Sex differences in treatment and outcome after stroke: pooled analysis including 19,000 participants

C Carcel, X Wang, EC Sandset, C Delcourt, H Arima… - Neurology, 2019 - AAN Enterprises
Objective To explore the sex differences in outcomes and management after stroke using a
large sample with high-quality international trial data. Methods Individual participant data …

Sex differences in long-term quality of life among survivors after stroke in the INSTRUCT

HT Phan, CL Blizzard, MJ Reeves, AG Thrift… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Women are reported to have poorer health-related quality of life
(HRQoL) after stroke than men, but the underlying reasons are uncertain. We investigated …

Sex differences in severity of stroke in the INSTRUCT study: a meta‐analysis of individual participant data

HT Phan, MJ Reeves, CL Blizzard… - Journal of the …, 2019 - Am Heart Assoc
Background Women have worse outcomes after stroke than men, and this may be partly
explained by stroke severity. We examined factors contributing to sex differences in severity …

Prestroke sarcopenia and functional outcomes in elderly patients who have had an acute stroke: A prospective cohort study

M Nozoe, M Kanai, H Kubo, M Yamamoto, S Shimada… - Nutrition, 2019 - Elsevier
Objectives The association between prestroke sarcopenia and functional outcomes in
patients who have had a stroke has not, to our knowledge, been evaluated to date. We …

Sex differences in IV thrombolysis treatment for acute ischemic stroke: a systematic review and meta-analysis

B Strong, LD Lisabeth, M Reeves - Neurology, 2020 - AAN Enterprises
Objective A prior meta-analysis of reports published between 2000 and 2008 found that
women were 30% less likely to receive IV recombinant tissue plasminogen activator (rtPA) …

Stroke in women: When gender matters

Q Thomas, V Crespy, G Duloquin, M Ndiaye… - Revue …, 2021 - Elsevier
Stroke in women may be considered as a distinct entity due to numerous differences
compared with men, including specific epidemiological, etiological, and outcome features …

Sex differences in outcome after thrombectomy for acute ischemic stroke are explained by confounding factors

M Deb-Chatterji, E Schlemm, F Flottmann, L Meyer… - Clinical …, 2021 - Springer
Purpose The aim of this study was to analyze sex differences in outcome after thrombectomy
for acute ischemic stroke in clinical practice in a large prospective multicenter registry …