Abstract Purpose of Review This review aims to examine (i) the aetiology of obesity;(ii) how
and why a perception of personal responsibility for obesity so dominantly frames this …

The discovery of leptin changed the view of adipose tissue from that of a passive vessel that
stores fat to that of a dynamic endocrine organ that actively regulates behaviour and …

Severe obesity is a rapidly growing global health threat. Although often attributed to
unhealthy lifestyle choices or environmental factors, obesity is known to be heritable and …

This review considers a variety of perspectives on overweight and obesity (OW/obesity),
including measurement and classification; prevalence and changes in prevalence in recent …

The worldwide prevalence of obesity more than doubled between 1980 and 2014. The
obesity pandemic is tightly linked to an increase in energy availability, sedentariness and …

Leptin is an adipose tissue hormone that functions as an afferent signal in a negative
feedback loop that maintains homeostatic control of adipose tissue mass. This endocrine …

Obesity is a highly heritable disease driven by complex interactions between genetic and
environmental factors. Human genome-wide association studies (GWAS) have identified a …

Human nutrition is a branch of medicine based on foods biochemical interactions with the
human body. The phenotypic transition from health to disease status can be attributed to …

Obesity is defined medically as a state of increased body weight, more specifically adipose
tissue, of sufficient magnitude to produce adverse health consequences. There has been an …

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