Abstract Type 2 diabetes (T2D) and Alzheimer's disease (AD) are two age‐related amyloid
diseases that affect millions of people worldwide. Broadly supported by epidemiological …

Organophosphate is a commonly used pesticide in the agricultural sector. The main action
of organophosphate focuses on acetylcholinesterase inhibition, and it therefore contributes …

Ingestion of a meal is the greatest challenge faced by glucose homeostasis. The surge of
nutrients has to be disposed quickly, as high concentrations in the bloodstream may have …

The hypotheses were: HISS-dependent insulin resistance (HDIR) accounts for insulin
resistance that occurs with aging; HDIR is the initiating metabolic defect that leads …

Different diets have distinct impacts on glucose homoeostasis, for which insulin sensitivity
(IS) after a meal (postprandial IS) is highly relevant. Postprandial IS depends upon hepatic …

The dynamic response to insulin is highly potentiated after meal ingestion, and this meal-
induced insulin sensitization (MIS) in healthy subjects is dependent on cholinergic …

Globally diabetes mellitus has become a medical problem with an increase in prevalence,
morbidity and mortality. To date, it has no cure yet, however, medical care, healthy life style …

Dyslipidemia is one of the most common complications in diabetes mellitus, which increases
risk of premature atherosclerosis. Drugs having antihyperlipidemic activity in addition to their …

A series of in vivo and in vitro studies using animal and human models in the past 15 years
have demonstrated that approximately 55%(~ 66% in humans) of the glucose disposal effect …

Hepatalin is a hormone secreted by the liver in response to pulses of insulin after a mixed
nutrient meal, but only if the liver receives two permissive synergistic feeding signals from …