Cardiovascular complications of immune checkpoint inhibitors for cancer
Over the last decade or so, there has been a paradigm shift in the oncologic care of patients
with a range of solid tumour and haematologic malignancies, away from traditional cytotoxic …
with a range of solid tumour and haematologic malignancies, away from traditional cytotoxic …
Predictive biomarkers for checkpoint inhibitor immune-related adverse events
I Les, M Martinez, I Perez-Francisco, M Cabero… - Cancers, 2023 - mdpi.com
Simple Summary Immune-checkpoint inhibitors (ICIs) are increasingly used in the treatment
of cancer, but they cause immune-related adverse events (irAEs) in around 40% of patients …
of cancer, but they cause immune-related adverse events (irAEs) in around 40% of patients …
Mechanisms driving immune-related adverse events in cancer patients treated with immune checkpoint inhibitors
Abstract Purpose of Review In the past decade, immune checkpoint inhibitors (ICIs) have
revolutionized the field of cancer treatment. With the continuing rise in the number of cancer …
revolutionized the field of cancer treatment. With the continuing rise in the number of cancer …
Neutrophil-to-lymphocyte ratio an inflammatory biomarker, and prognostic marker in heart failure, cardiovascular disease and chronic inflammatory diseases: New …
A García-Escobar, S Vera-Vera, D Tébar-Márquez… - Microvascular …, 2023 - Elsevier
In the 20th century, research focused on cholesterol and lipoproteins as the key mechanism
in establishing atherosclerotic cardiovascular disease (ASCVD). Given that some studies …
in establishing atherosclerotic cardiovascular disease (ASCVD). Given that some studies …
[HTML][HTML] Pericardial disease in patients treated with immune checkpoint inhibitors
J Gong, ZD Drobni, A Zafar, T Quinaglia… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background There are limited data on the occurrence, associations and outcomes of
pericardial effusions and pericarditis on or after treatment with immune checkpoint inhibitors …
pericardial effusions and pericarditis on or after treatment with immune checkpoint inhibitors …
Neutrophil to Lymphocyte ratio as a predictor for immune-related adverse events in cancer patients treated with immune checkpoint inhibitors: a systematic review and …
W Zhang, Y Tan, Y Li, J Liu - Frontiers in Immunology, 2023 - frontiersin.org
Background The use of immune checkpoint inhibitors (ICIs) in cancer treatment has led to an
increase in immune-related adverse events (irAEs), which can cause treatment …
increase in immune-related adverse events (irAEs), which can cause treatment …
Peripheral blood biomarkers for early diagnosis, severity, and prognosis of checkpoint inhibitor-related pneumonitis in patients with lung cancer
X Lin, H Deng, Y Yang, J Wu, G Qiu, S Li, X Xie… - Frontiers in …, 2021 - frontiersin.org
Background Checkpoint inhibitor-related pneumonitis (CIP) is a potentially fatal immune-
related adverse event that occurs during treatment with immune checkpoint inhibitors (ICIs) …
related adverse event that occurs during treatment with immune checkpoint inhibitors (ICIs) …
Mediators and mechanisms of immune checkpoint inhibitor‐associated myocarditis: Insights from mouse and human
J Gong, TG Neilan, DA Zlotoff - Immunological Reviews, 2023 - Wiley Online Library
The broad application of immune checkpoint inhibitors (ICIs) has led to significant gains in
cancer outcomes. By abrogating inhibitory signals, ICIs promote T cell targeting of cancer …
cancer outcomes. By abrogating inhibitory signals, ICIs promote T cell targeting of cancer …
[HTML][HTML] Correlations between peripheral blood biomarkers and clinical outcomes in advanced non-small cell lung cancer patients who received immunotherapy …
Y Shi, X Liu, J Liu, D Zhang, X Liu, Y Yue… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Background Peripheral blood-based biomarkers (PBB) predicting response, survival and
immune-related adverse events (irAEs) in patients with advanced non-small cell lung cancer …
immune-related adverse events (irAEs) in patients with advanced non-small cell lung cancer …
Fractalkine/CX3CR1 in Dilated Cardiomyopathy: A Potential Future Target for Immunomodulatory Therapy?
V Jeyalan, D Austin, SX Loh, VK Wangsaputra… - Cells, 2023 - mdpi.com
Dilated cardiomyopathy (DCM) is a cardiac condition with structural and functional
impairment, where either the left ventricle or both ventricular chambers are enlarged …
impairment, where either the left ventricle or both ventricular chambers are enlarged …