The cerebrospinal fluid (CSF) is a complex solution that circulates around the CNS, and
whose composition changes as a function of an animal's physiological state. Ciliated …

Scoliosis is a common spinal deformity that considerably affects the physical and
psychological health of patients. Studies have shown that genetic factors play an important …

Defects in cerebrospinal fluid (CSF) flow may contribute to idiopathic scoliosis. However, the
mechanisms underlying detection of CSF flow in the central canal of the spinal cord are …

Straightening of the body axis is a major morphogenetic event that produces the typical
head-to-tail shape of the vertebrate embryo. Defects in axial straightening can lead to …

The pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) can invade the
cerebrospinal fluid (CSF) and cause meningitis with devastating consequences. Whether …

The spine provides structure and support to the body, yet how it develops its characteristic
morphology as the organism grows is little understood. This is underscored by the …

Recent evidence indicates active roles for the cerebrospinal fluid (CSF) on body axis
development and morphogenesis of the spine, implying CSF-contacting neurons (CSF-cNs) …

The vertebrate body plan is characterized by the presence of a segmented spine along its
main axis. Here, we examine the current understanding of how the axial tissues that are …

The cerebrospinal fluid (CSF) constitutes an interface through which chemical cues can
reach and modulate the activity of neurons located at the epithelial boundary within the …

Urp1 and Urp2 are two neuropeptides, members of the Urotensin 2 family, that have been
recently involved in the control of body axis morphogenesis in zebrafish. They are produced …