Biomarkers Associated With Leishmania infantum Exposure, Infection, and Disease in Dogs

C Maia, L Campino - Frontiers in cellular and infection microbiology, 2018 - frontiersin.org
Canine leishmaniosis (CanL) is a vector-borne disease caused by the protozoan
Leishmania (Leishmania) infantum species [syn. L.(L.) infantum chagasi species in the …

Insights on adaptive and innate immunity in canine leishmaniosis

S Hosein, DP Blake, L Solano-Gallego - Parasitology, 2017 - cambridge.org
Canine leishmaniosis (CanL) is caused by the parasite Leishmania infantum and is a
systemic disease, which can present with variable clinical signs, and clinicopathological …

From infection to death: an overview of the pathogenesis of Visceral Leishmaniasis

CHN Costa, KP Chang, DL Costa, FVM Cunha - Pathogens, 2023 - mdpi.com
Kala-azar, also known as visceral leishmaniasis (VL), is a disease caused by Leishmania
infantum and L. donovani. Patients experience symptoms such as fever, weight loss …

Effects of visceralising Leishmania on the spleen, liver, and bone marrow: a pathophysiological perspective

A Poulaki, ET Piperaki, M Voulgarelis - Microorganisms, 2021 - mdpi.com
The leishmaniases constitute a group of parasitic diseases caused by species of the
protozoan genus Leishmania. In humans it can present different clinical manifestations and …

Histological disorganization of spleen compartments and severe visceral leishmaniasis

MER Hermida, CVB De Melo, IS Lima… - Frontiers in cellular …, 2018 - frontiersin.org
The spleen is a secondary lymphoid organ responsible for immune surveillance against
blood-circulating pathogens. Absence of the spleen is associated with increased …

The contribution of immune evasive mechanisms to parasite persistence in visceral leishmaniasis

EO De Freitas, FMS Leoratti… - Frontiers in …, 2016 - frontiersin.org
Leishmania is a genus of protozoan parasites that give rise to a range of diseases called
Leishmaniasis that affects annually an estimated 1.3 million people from 88 countries …

Canine visceral leishmaniasis biomarkers and their employment in vaccines

RC Giunchetti, P Silveira, LA Resende, JC Leite… - Veterinary …, 2019 - Elsevier
The natural history of canine visceral leishmaniasis (CVL) has been well described,
particularly with respect to the parasite load in different tissues and immunopathological …

Using Proteomics to Understand How Leishmania Parasites Survive inside the Host and Establish Infection

PST Veras, JP Bezerra de Menezes - International Journal of Molecular …, 2016 - mdpi.com
Leishmania is a protozoan parasite that causes a wide range of different clinical
manifestations in mammalian hosts. It is a major public health risk on different continents …

[HTML][HTML] Is Leishmania (Viannia) braziliensis parasite load associated with disease pathogenesis?

LOR Pereira, RB Moreira, MP de Oliveira… - International Journal of …, 2017 - Elsevier
Summary Background Leishmania (Viannia) braziliensis is the main etiological agent of
tegumentary leishmaniasis in the Americas. Parasite molecular diversity and host immune …

PD-1 function in apoptosis of T lymphocytes in canine visceral leishmaniasis

VM Chiku, KLO Silva, BFM de Almeida, GL Venturin… - Immunobiology, 2016 - Elsevier
Dogs infected with Leishmania infantum have a reduced number of T lymphocytes. PD-1
(Programmed cell death 1) a new member of the B7-CD28 family that is expressed by …