Mechanisms of botulinum toxin type A action on pain
Already a well-established treatment for different autonomic and movement disorders, the
use of botulinum toxin type A (BoNT/A) in pain conditions is now continuously expanding …
use of botulinum toxin type A (BoNT/A) in pain conditions is now continuously expanding …
Botulinum toxin for neuropathic pain: a review of the literature
HM Oh, ME Chung - Toxins, 2015 - mdpi.com
Botulinum neurotoxin (BoNT), derived from Clostridium botulinum, has been used
therapeutically for focal dystonia, spasticity, and chronic migraine. Its spectrum as a potential …
therapeutically for focal dystonia, spasticity, and chronic migraine. Its spectrum as a potential …
Botulinum toxin A, brain and pain
I Matak, Z Lacković - Progress in neurobiology, 2014 - Elsevier
Botulinum neurotoxin type A (BoNT/A) is one of the most potent toxins known and a potential
biological threat. At the same time, it is among the most widely used therapeutic proteins …
biological threat. At the same time, it is among the most widely used therapeutic proteins …
Botulinum toxin-A effects on pain, somatosensory and psychosocial features of patients with refractory masticatory myofascial pain: a randomized double-blind clinical …
G De la Torre Canales, RL Poluha, LR Bonjardim… - Scientific Reports, 2024 - nature.com
The antinociceptive effect of BoNT-A have been well documented in animal studies;
however, results of few but well-designed randomized placebo-controlled clinical trials …
however, results of few but well-designed randomized placebo-controlled clinical trials …
Long-term effects of a single application of botulinum toxin type A in temporomandibular myofascial pain patients: A controlled clinical trial
G De la Torre Canales, MB Câmara-Souza, RL Poluha… - Toxins, 2022 - mdpi.com
This study assessed the long-term effects of botulinum toxin type A (BoNT-A) in subjective
pain, pain sensibility, and muscle thickness in persistent myofascial temporomandibular …
pain, pain sensibility, and muscle thickness in persistent myofascial temporomandibular …
Botulinum toxin type a as a therapeutic agent against headache and related disorders
Botulinum neurotoxin A (BoNT/A) is a toxin produced by the naturally-occurring Clostridium
botulinum that causes botulism. The potential of BoNT/A as a useful medical intervention …
botulinum that causes botulism. The potential of BoNT/A as a useful medical intervention …
Botulinum toxin: a review of the mode of action in migraine
Botulinum toxin serotype A (Bo NT/A) was originally used in neurology for the treatment of
dystonia and blepharospasms, but is now clinically used worldwide for the treatment of …
dystonia and blepharospasms, but is now clinically used worldwide for the treatment of …
[HTML][HTML] Involvement of substance P in the antinociceptive effect of botulinum toxin type A: Evidence from knockout mice
The antinociceptive action of botulinum toxin type A (BoNT/A) has been demonstrated in
behavioral animal studies and clinical settings. It was shown that this effect is associated …
behavioral animal studies and clinical settings. It was shown that this effect is associated …
Effects of botulinum toxin type A on the nociceptive and lemniscal somatosensory systems in chronic migraine: an electrophysiological study
G Sebastianelli, F Casillo, A Di Renzo, C Abagnale… - Toxins, 2023 - mdpi.com
(1) Background: OnabotulinumtoxinA (BoNT-A) is a commonly used prophylactic treatment
for chronic migraine (CM). Although randomized placebo studies have shown its clinical …
for chronic migraine (CM). Although randomized placebo studies have shown its clinical …
Botulinum toxin B in the sensory afferent: transmitter release, spinal activation, and pain behavior
MJ Marino, T Terashima, JJ Steinauer, KA Eddinger… - PAIN®, 2014 - Elsevier
We addressed the hypothesis that intraplantar botulinum toxin B (rimabotulinumtoxin B:
BoNT-B) has an early local effect upon peripheral afferent terminal releasing function and …
BoNT-B) has an early local effect upon peripheral afferent terminal releasing function and …