Piezo-type mechanosensitive ion channel component 1 (Piezo1) is a mechanosensitive ion
channel protein that is evolutionarily conserved and multifunctional. It plays an important …

Abstract Non‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a
unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) …

Chondrocyte mechanotransduction is not well understood, but recently, it has been
proposed that mechanically activated ion channels such as transient receptor potential …

Cells sense and respond to extracellular mechanical stress through mechanotransduction
receptors and ion channels, which regulate cellular behaviors such as cell proliferation and …

Background. Piezo1/2, a mechanically activated ion channel, is believed to play an
important role in bladder carcinogenesis process. Piezo1/2 expression has not been …

Human body is subject to many and variegated mechanical stimuli, actuated in different
ranges of force, frequency, and duration. The process through which cells “feel” forces and …

Angiogenesis is important for invasive tumor growth and metastasis. Its inhibition is a
promising tactic for limiting tumor progression. Here, we showed that Piezo2 knockdown led …

Fibrosis could happen in every organ, leading to organic malfunction and even organ
failure, which poses a serious threat to global health. Early treatment of fibrosis has been …

Wearable devices (wearables) have recently gained significant traction and are predicted to
dominate many areas of research over the next 5 years. Many wearables contain a host of …

Two PIEZO mechanosensitive cation channels, PIEZO1 and PIEZO2, have been identified in
mammals, where they are involved in numerous sensory processes. While structurally …