Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …

Achieving sufficient delivery across the blood–brain barrier is a key challenge in the
development of drugs to treat central nervous system (CNS) disorders. This is particularly …

The ability of cells to transmit bioactive molecules to recipient cells and the extracellular
environment is a fundamental requirement for both normal physiology and disease …

Cancer patients have an increased risk of venous thromboembolism (VTE). In this review,
we summarize common and cancer type–specific pathways of VTE in cancer patients …

Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into
their environment. Why do cells release vesicles? Initial studies showed that eukaryotic …

The small vesicles shed from the surface of many cells upon stimulation, considered for a
long time to be artefacts, are now recognized as specific structures that are distinct from the …

M tivities seem to work in concert to maintain a nonrandom ANY STUDIES HAVE led to the
concept that membrane phospholipid asymmetry is ubiquitous. In gen- transbilayer …

Microvesicles are nano-sized lipid vesicles released by all cells in vivo and in vitro. They are
released physiologically under normal conditions but their rate of release is higher under …

Several studies have suggested a role for blood coagulation proteins in tumour progression.
Herein, we discuss (1) the activation of the blood clotting cascade in the tumour …

The study of tumor biology has, in recent years, focused on the abnormal regulation of
growth control an neoplastic cells and on the genes that control tumor cell proliferation …