Antiphospholipid syndrome: advances in diagnosis, pathogenesis, and management

JS Knight, DW Branch, TL Ortel - bmj, 2023 - bmj.com
Antiphospholipid syndrome (APS) is a thrombo-inflammatory disease propelled by
circulating autoantibodies that recognize cell surface phospholipids and phospholipid …

Antiphospholipid syndrome

LR Sammaritano - Best Practice & Research Clinical Rheumatology, 2020 - Elsevier
Antiphospholipid syndrome is an autoimmune systemic disorder characterized by arterial,
venous, or small vessel thrombosis and/or recurrent early pregnancy loss, fetal loss, or …

Management of antiphospholipid syndrome

I Uthman, MHA Noureldine, G Ruiz-Irastorza… - Annals of the …, 2019 - ard.bmj.com
Antiphospholipid syndrome, also known as 'Hughes Syndrome', is an autoimmune disease
characterised by a set of clinical manifestations, almost all of which are direct or indirect …

Antiphospholipid syndrome management: a 2023 update and practical algorithm-based approach

A Ambati, JS Knight, Y Zuo - Current opinion in rheumatology, 2023 - journals.lww.com
Although the knowledge of APS pathogenesis has grown in recent years, the management
principles and strategies are largely unchanged. There is an unmet need for evaluating …

Antithrombotic Therapy to Prevent Recurrent Strokes in Ischemic Cerebrovascular Disease: JACC Scientific Expert Panel

VJ Del Brutto, S Chaturvedi, HC Diener… - Journal of the American …, 2019 - jacc.org
Stroke survivors carry a high risk of recurrence. Antithrombotic medications are paramount
for secondary prevention and thus crucial to reduce the overall stroke burden. Appropriate …

The treatment of anti-phospholipid syndrome: a comprehensive clinical approach

CB Chighizola, L Andreoli, M Gerosa, A Tincani… - Journal of …, 2018 - Elsevier
Anti-phospholipid syndrome (APS) is an acquired pro-thrombotic autoimmune disease that
predisposes to thrombotic events and/or obstetric complications, in the persistent presence …

Antiphospholipid syndrome: a clinical perspective

Y Zuo, H Shi, C Li, JS Knight - Chinese Medical Journal, 2020 - mednexus.org
Antiphospholipid syndrome (APS) is a thromboinflammatory disease with a variety of clinical
phenotypes. Primary thrombosis prophylaxis should take an individualized risk stratification …

Lipoxin A4 restores oxidative stress-induced vascular endothelial cell injury and thrombosis-related factor expression by its receptor-mediated activation of Nrf2-HO-1 …

S Yang, Y Zheng, X Hou - Cellular Signalling, 2019 - Elsevier
Venous thromboembolism (VTE) constitutes a common cause of hospital-related morbidity
and mortality, with the proverbial clinical feature of deep venous thrombosis (DVT) …

[HTML][HTML] Patterns of recurrent thrombosis in primary antiphospholipid syndrome—multicenter, real-life long-term follow-up

S Niznik, MJ Rapoport, O Avnery, A Lubetsky… - Frontiers in …, 2022 - frontiersin.org
Background Antiphospholipid syndrome (APS) is an acquired hypercoagulable condition
associated with antiphospholipid antibody (aPL) presence. Data on re-thrombosis following …

Antiphospholipid syndrome: a clinical review

V Mezhov, JD Segan, H Tran, FM Cicuttini - The Medical Journal of …, 2019 - mja.com.au
Antiphospholipid syndrome is characterised by recurrent thrombosis (arterial, venous,
microvascular) and/or pregnancy complications in the presence of persistent …