Cells live in a chemical environment and are able to orient towards chemical cues.
Unicellular haploid fungal cells communicate by secreting pheromones to reproduce …

Accurate decoding of spatial chemical landscapes is critical for many cell functions.
Eukaryotic cells decode local chemical gradients to orient growth or movement in productive …

Fungi exhibit an enormous variety of morphologies, including yeast colonies, hyphal
mycelia, and elaborate fruiting bodies. This diversity arises through a combination of polar …

How small eukaryotic cells can interpret dynamic, noisy, and spatially complex chemical
gradients to orient growth or movement is poorly understood. We address this question …

Directed cell growth or migration are critical for the development and function of many
eukaryotic cells. These cells develop a dynamic “front”(also called “polarity site”) that can …

Yeast decode pheromone gradients to locate mating partners, providing a model for
chemotropism. How yeast polarize toward a single partner in crowded environments is …

In response to pheromone Saccharomyces cerevisiae extend a mating projection. This
process depends on the formation of polarized actin cables which direct secretion to the …

Cells in natural environments, such as tissue or soil, sense and respond to extracellular
ligands with intricately structured and non-monotonic spatial distributions, sculpted by …

Many cells adjust the direction of polarized growth or migration in response to external
directional cues. The yeast Saccharomyces cerevisiae orient their cell fronts (also called …

Haploid cells of the budding yeast Saccharomyces cerevisiae communicate using secreted
pheromones and mate to form diploid zygotes. Mating is monogamous, resulting in the …