Quantitative magnetic resonance imaging towards clinical application in multiple sclerosis

C Granziera, J Wuerfel, F Barkhof, M Calabrese… - Brain, 2021 - academic.oup.com
Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

A neuroradiologist's guide to arterial spin labeling MRI in clinical practice

M Grade, JA Hernandez Tamames, FB Pizzini… - Neuroradiology, 2015 - Springer
Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

Optical coherence tomography angiography measurements in multiple sclerosis: a systematic review and meta-analysis

S Mohammadi, M Gouravani, MA Salehi… - Journal of …, 2023 - Springer
Background and objectives Recent literature on multiple sclerosis (MS) demonstrates the
growing implementation of optical coherence tomography–angiography (OCT-A) to discover …

Mind the gap: from neurons to networks to outcomes in multiple sclerosis

DT Chard, AAS Alahmadi, B Audoin… - Nature Reviews …, 2021 - nature.com
MRI studies have provided valuable insights into the structure and function of neural
networks, particularly in health and in classical neurodegenerative conditions such as …

Nonconventional MRI and microstructural cerebral changes in multiple sclerosis

C Enzinger, F Barkhof, O Ciccarelli, M Filippi… - Nature Reviews …, 2015 - nature.com
MRI has become the most important paraclinical tool for diagnosing and monitoring patients
with multiple sclerosis (MS). However, conventional MRI sequences are largely nonspecific …

Arterial spin labeling for the measurement of cerebral perfusion and angiography

P Jezzard, MA Chappell… - Journal of Cerebral Blood …, 2018 - journals.sagepub.com
Arterial spin labeling (ASL) is an MRI technique that was first proposed a quarter of a century
ago. It offers the prospect of non-invasive quantitative measurement of cerebral perfusion …

Understanding a role for hypoxia in lesion formation and location in the deep and periventricular white matter in small vessel disease and multiple sclerosis

S Martinez Sosa, KJ Smith - Clinical Science, 2017 - portlandpress.com
The deep and periventricular white matter is preferentially affected in several neurological
disorders, including cerebral small vessel disease (SVD) and multiple sclerosis (MS) …

The spatial coefficient of variation in arterial spin labeling cerebral blood flow images

HJMM Mutsaerts, J Petr, L Václavů… - Journal of Cerebral …, 2017 - journals.sagepub.com
Macro-vascular artifacts are a common arterial spin labeling (ASL) finding in populations
with prolonged arterial transit time (ATT) and result in vascular regions with spuriously …

Cause and prevention of demyelination in a model multiple sclerosis lesion

RA Desai, AL Davies, M Tachrount, M Kasti… - Annals of …, 2016 - Wiley Online Library
Objective Demyelination is a cardinal feature of multiple sclerosis, but it remains unclear
why new lesions form, and whether they can be prevented. Neuropathological evidence …

Optical coherence tomography angiography findings of multiple sclerosis with or without optic neuritis

MO Ulusoy, B Horasanlı, S Işık-Ulusoy - Neurological research, 2020 - Taylor & Francis
Objective: Nowadays, retinal microvascular structures can be investigated using optical
coherence tomography angiography (OCTA). We aimed to evaluate the probable vascular …