Environmental risks of pharmaceutical mixtures in aquatic ecosystems: Reflections on a decade of research

KA Kidd, T Backhaus, T Brodin… - Environmental …, 2024 - Wiley Online Library
Pharmaceuticals and personal care products (PPCPs) occur as variable mixtures in surface
waters receiving discharges of human and animal wastes. A key question identified a …

Freshwater crustacean exposed to active pharmaceutical ingredients: ecotoxicological effects and mechanisms

J Guo, J Ren, C Chang, Q Duan, J Li… - … Science and Pollution …, 2023 - Springer
Concerns over the ecotoxicological effects of active pharmaceutical ingredients (APIs) on
aquatic invertebrates have been raised in the last decade. While numerous studies have …

Ketoprofen affects swimming behavior and impairs physiological endpoints of Daphnia magna

A Bownik, M Jasieczek, E Kosztowny - Science of the Total Environment, 2020 - Elsevier
Ketoprofen (KET) is a nonsteroidal anti-inflammatory and analgesic drug commonly used in
human and veterinary medicine. This compound is detected in aquatic reservoirs however …

Effects of butyl benzyl phthalate exposure on Daphnia magna growth, reproduction, embryonic development and transcriptomic responses

J Li, H Li, D Lin, M Li, Q Wang, S Xie, Y Zhang… - Journal of Hazardous …, 2021 - Elsevier
Butyl benzyl phthalate (BBP) is widely used as a plasticizer to increase the plasticity and
flexibility of plastic products. Although the potential health hazards of BBP have recently …

Characterization of neurotransmitters and related metabolites in Daphnia magna juveniles deficient in serotonin and exposed to neuroactive chemicals that affect its …

I Fuertes, C Barata - Chemosphere, 2021 - Elsevier
Neurotransmitters are endogenous metabolites that play a crucial role within an organism, at
the chemical synapses. There is a growing interest in their analytical determination for …

[HTML][HTML] Toxicogenomic differentiation of functional responses to fipronil and imidacloprid in Daphnia magna

J Pfaff, H Reinwald, SU Ayobahan, J Alvincz… - Aquatic Toxicology, 2021 - Elsevier
Active substances of pesticides, biocides or pharmaceuticals can induce adverse side
effects in the aquatic ecosystem, necessitating environmental hazard and risk assessment …

An In Vivo Whole-Transcriptomic Approach to Assess Developmental and Reproductive Impairments Caused by Flumequine in Daphnia magna

E Pietropoli, M Pauletto, R Tolosi, S Iori… - International Journal of …, 2023 - mdpi.com
Among veterinary antibiotics, flumequine (FLU) is still widely used in aquaculture due to its
efficacy and cost-effectiveness. Although it was synthesized more than 50 years ago, a …

Changes in lipid profiles in Daphnia magna individuals exposed to low environmental levels of neuroactive pharmaceuticals

I Fuertes, B Piña, C Barata - Science of the Total Environment, 2020 - Elsevier
Disruptive effects of chemicals on lipids in aquatic species are mostly limited to obesogens
and vertebrates. Recent studies reported that antidepressants, anxiolytic, antiepileptic and β …

Transcriptomic responses to cytotoxic drug cisplatin in water flea Daphnia magna

J Ren, F Yang, N Ding, J Mo, J Guo - Environmental Toxicology and …, 2022 - Elsevier
Cytotoxic drugs have been recognized by the European Union as the potential threat in the
aquatic environment. As a typical cytotoxic drug, effects of long-term exposure to cisplatin at …

Investigating the toxically homogenous effects of three lanthanides on zebrafish

Z Huang, N Gao, S Zhang, J Xing, J Hou - Comparative Biochemistry and …, 2022 - Elsevier
The adverse effects of rare earth elements (REEs) have been increasingly reported in the
past decades and have raised concern about their environmental toxicities. However, the …