Evaluation of the binding effect and cytotoxicity assay of 2‐Ethyl‐5‐(4‐methylphenyl) pyramido pyrazole ophthalazine trione on calf thymus DNA: spectroscopic …

N Marjani, M Dareini, M Asadzade‐Lotfabad… - …, 2022 - Wiley Online Library
With advances in new drug therapies, it is essential to understand the interactions between
drugs and target molecules. In this study, we applied multiple spectroscopic techniques …

DNA binding studies of antifungal drug posaconazole using spectroscopic and molecular docking methods

SR Madku, BK Sahoo, K Lavanya, RS Reddy… - International Journal of …, 2023 - Elsevier
The binding studies of DNA with small molecules have been an emerging field of research
all the time since DNA as the genetic material is a major biological target for various drugs …

A new zinc (II) complex of 2-benzoimidazoledisulfide ligand: synthesis, X-ray crystallographic structure, investigation of CT-DNA and BSA interaction by spectroscopic …

F Mohammadlou, H Mansouri-Torshizi… - … of Photochemistry and …, 2023 - Elsevier
This study reports a new zinc (II) complex based on 2-mercaptobenzimidazole ligand. It was
synthesized and characterized by UV–visible and Fourier transform infrared spectroscopy …

In-vitro evaluation of apoptotic effect of OEO and thymol in 2D and 3D cell cultures and the study of their interaction mode with DNA

T Jamali, G Kavoosi, M Safavi, SK Ardestani - Scientific Reports, 2018 - nature.com
Oliveria decumbens is an Iranian endemic plant used extensively in traditional medicine.
Recently, some studies have been performed on biological effects of Oliveria essential oil …

Synthesis, structural characterization, molecular docking and DNA binding studies of copper complexes

IM El-Deen, AF Shoair, MA El-Bindary - Journal of molecular liquids, 2018 - Elsevier
Azo pyrazolones and their copper (II) complexes were characterized by elemental analyses,
IR, 1 H NMR, UV–Visible and magnetic measurements as well as thermal analysis and X …

Superstructure-dependent loading of DNA origami nanostructures with a groove-binding drug

F Kollmann, S Ramakrishnan, B Shen… - ACS …, 2018 - ACS Publications
DNA origami nanostructures are regarded as powerful and versatile vehicles for targeted
drug delivery. So far, DNA origami-based drug delivery strategies mostly use intercalation of …

Targeting natural polymeric DNAs with harmane: An insight into binding and thermodynamic interaction through biophysical approach

S Luikham, J Bhattacharyya - DNA and Cell Biology, 2022 - liebertpub.com
DNA is one of the major molecular targets for a broad range of anticancer drugs. Hence,
interaction studies involving cellular DNA and small molecules can be highly beneficial as …

Multi-spectroscopic and free energy landscape analysis on the binding of antiviral drug remdesivir with calf thymus DNA

RD Priyadharshini, S Ponkarpagam, KN Vennila… - … Acta Part A: Molecular …, 2022 - Elsevier
Remdesivir (REM) is an antiviral drug, which exercises its effect by targeting specifically
RNA-dependent RNA polymerase. The interaction of REM with calf thymus DNA (CT-DNA) …

Astaxanthin binding affinity to DNA: Studied by fluorescence, surface plasmon resonance and molecular docking methods

F Ranjbary, F Fathi, PS Pakchin, S Maleki - Journal of Fluorescence, 2024 - Springer
Carotenoid astaxanthin (Ax), a pink-red pigment, with its anti-oxidative feature, is useful as a
therapeutic element for numerous diseases. The purpose of this study is to investigate the …

Preparation of a highly stable drug carrier by efficient immobilization of human serum albumin (HSA) on drug-loaded magnetic iron oxide nanoparticles

NH Moghadam, S Salehzadeh, J Rakhtshah… - International journal of …, 2019 - Elsevier
Albumin immobilized nanoparticles are known to be biodegradable, easy to prepare and
reproducible for drug delivery systems. In summary, we have synthesized a new drug carrier …