Role of fibroblasts and myofibroblasts on the pathogenesis and treatment of pelvic organ prolapse
Z Guler, JP Roovers - Biomolecules, 2022 - mdpi.com
Pelvic organ prolapse (POP) is a multifactorial connective tissue disorder caused by
damage to the supportive structures of the pelvic floor, leading to the descent of pelvic …
damage to the supportive structures of the pelvic floor, leading to the descent of pelvic …
Polypropylene pelvic mesh: What went wrong and what will be of the future?
A Seifalian, Z Basma, A Digesu, V Khullar - Biomedicines, 2023 - mdpi.com
Background: Polypropylene (PP) pelvic mesh is a synthetic mesh made of PP polymer used
to treat pelvic organ prolapse (POP). Its use has become highly controversial due to reports …
to treat pelvic organ prolapse (POP). Its use has become highly controversial due to reports …
3D bioprinted endometrial stem cells on melt electrospun poly ε-caprolactone mesh for pelvic floor application promote anti-inflammatory responses in mice
Endometrial mesenchymal stem/stromal cells (eMSCs) exhibit excellent regenerative
capacity in the endometrial lining of the uterus following menstruation and high proliferative …
capacity in the endometrial lining of the uterus following menstruation and high proliferative …
Host response to synthetic mesh in women with mesh complications
Background Despite good anatomic and functional outcomes, urogynecologic
polypropylene meshes that are used to treat pelvic organ prolapse and stress urinary …
polypropylene meshes that are used to treat pelvic organ prolapse and stress urinary …
Modeling the flow behavior and flow rate of medium viscosity alginate for scaffold fabrication with a three-dimensional bioplotter
Tissue regeneration with scaffolds has proven promising for the repair of damaged tissues
or organs. Dispensing-based printing techniques for scaffold fabrication have drawn …
or organs. Dispensing-based printing techniques for scaffold fabrication have drawn …
Development and biomechanical testing of artificial surrogates for vaginal tissue
Millions of women around the globe have been affected by inadequately assessed
gynaecological surgeries and urogynaecology mesh implantations. The unavailability of …
gynaecological surgeries and urogynaecology mesh implantations. The unavailability of …
Mechanical biocompatibility of highly deformable biomedical materials
E Mazza, AE Ehret - Journal of the mechanical behavior of biomedical …, 2015 - Elsevier
Mismatch of mechanical properties between highly deformable biomedical materials and
adjacent native tissue might lead to short and long term health impairment. The capability of …
adjacent native tissue might lead to short and long term health impairment. The capability of …
Landmarks in vaginal mesh development: polypropylene mesh for treatment of SUI and POP
N Mangir, B Aldemir Dikici, CR Chapple… - Nature Reviews …, 2019 - nature.com
Vaginal meshes used in the treatment of stress urinary incontinence (SUI) and pelvic organ
prolapse (POP) have produced highly variable outcomes, causing life-changing …
prolapse (POP) have produced highly variable outcomes, causing life-changing …
Mesh deformation: A mechanism underlying polypropylene prolapse mesh complications in vivo
Polypropylene meshes used in pelvic organ prolapse (POP) repair are hampered by
complications. Most POP meshes are highly unstable after tensioning ex vivo, as evidenced …
complications. Most POP meshes are highly unstable after tensioning ex vivo, as evidenced …
Characterization of the host inflammatory response following implantation of prolapse mesh in rhesus macaque
Objective We sought to determine the predominant cell type (macrophage, T lymphocyte, B
lymphocyte, mast cell) within the area of implantation of the prototypical polypropylene …
lymphocyte, mast cell) within the area of implantation of the prototypical polypropylene …