Natural killer cells in cancer biology and therapy
SY Wu, T Fu, YZ Jiang, ZM Shao - Molecular cancer, 2020 - Springer
The tumor microenvironment is highly complex, and immune escape is currently considered
an important hallmark of cancer, largely contributing to tumor progression and metastasis …
an important hallmark of cancer, largely contributing to tumor progression and metastasis …
[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders
JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …
disorders and metabolic syndrome have largely been attributed to genetic background and …
Sarcopenic obesity or obese sarcopenia: a cross talk between age-associated adipose tissue and skeletal muscle inflammation as a main mechanism of the …
A Kalinkovich, G Livshits - Ageing research reviews, 2017 - Elsevier
Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …
Health consequences of sarcopenic obesity: a narrative review
E Roh, KM Choi - Frontiers in endocrinology, 2020 - frontiersin.org
Sarcopenia is defined as the age-related loss of muscle mass and strength or physical
performance. Increased amounts of adipose tissue often accompany sarcopenia, a condition …
performance. Increased amounts of adipose tissue often accompany sarcopenia, a condition …
Immune and non-immune functions of adipose tissue leukocytes
Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …
Much of the work into understanding the role of immune cells in adipose tissue has been in …
The role of infiltrating immune cells in dysfunctional adipose tissue
TJ Guzik, DS Skiba, RM Touyz… - Cardiovascular …, 2017 - academic.oup.com
Adipose tissue (AT) dysfunction, characterized by loss of its homeostatic functions, is a
hallmark of non-communicable diseases. It is characterized by chronic low-grade …
hallmark of non-communicable diseases. It is characterized by chronic low-grade …
Tissue immune cells fuel obesity-associated inflammation in adipose tissue and beyond
R Liu, BS Nikolajczyk - Frontiers in immunology, 2019 - frontiersin.org
Obesity-associated inflammation stems from a combination of cell-intrinsic changes of
individual immune cell subsets and the dynamic crosstalk amongst a broad array of immune …
individual immune cell subsets and the dynamic crosstalk amongst a broad array of immune …
Obesity and COVID-19: molecular mechanisms linking both pandemics
The coronavirus disease 2019 COVID-19 pandemic is rapidly spreading worldwide and is
becoming a major public health crisis. Increasing evidence demonstrates a strong …
becoming a major public health crisis. Increasing evidence demonstrates a strong …
Mitochondrial dysfunction in obesity
AH de Mello, AB Costa, JDG Engel, GT Rezin - Life sciences, 2018 - Elsevier
Obesity leads to various changes in the body. Among them, the existing inflammatory
process may lead to an increase in the production of reactive oxygen species (ROS) and …
process may lead to an increase in the production of reactive oxygen species (ROS) and …
Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus
Obesity and diabetes are the two major metabolic complications linked with bad eating
habits and the sedentary (lazy) lifestyle. In the worst-case situation, metabolic problems are …
habits and the sedentary (lazy) lifestyle. In the worst-case situation, metabolic problems are …