Allergen immunotherapy in children user's guide
Allergen immunotherapy is a cornerstone in the treatment of allergic children. The clinical
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …
efficiency relies on a well‐defined immunologic mechanism promoting regulatory T cells and …
Non‐specific lipid‐transfer proteins: Allergen structure and function, cross‐reactivity, sensitization, and epidemiology
Background Discovered and described 40 years ago, non‐specific lipid transfer proteins
(nsLTP) are present in many plant species and play an important role protecting plants from …
(nsLTP) are present in many plant species and play an important role protecting plants from …
EAACI molecular allergology user's guide 2.0
S Dramburg, C Hilger, AF Santos… - Pediatric Allergy and …, 2023 - Wiley Online Library
Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967,
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …
our knowledge about the immunological mechanisms of IgE‐mediated allergies has …
Molecular allergology and its impact in specific allergy diagnosis and therapy
Progressive knowledge of allergenic structures resulted in a broad availability of allergenic
molecules for diagnosis. Component‐resolved diagnosis allowed a better understanding of …
molecules for diagnosis. Component‐resolved diagnosis allowed a better understanding of …
Multi‐omics analysis points to altered platelet functions in severe food‐associated respiratory allergy
D Obeso, L Mera‐Berriatua, J Rodríguez‐Coira… - Allergy, 2018 - Wiley Online Library
Background Prevalence and severity of allergic diseases have increased worldwide. To
date, respiratory allergy phenotypes are not fully characterized and, along with inflammation …
date, respiratory allergy phenotypes are not fully characterized and, along with inflammation …
The importance of metabolism for immune homeostasis in allergic diseases
J Rodriguez-Coira, A Villaseñor, E Izquierdo… - Frontiers in …, 2021 - frontiersin.org
There is increasing evidence that the metabolic status of T cells and macrophages is
associated with severe phenotypes of chronic inflammation, including allergic inflammation …
associated with severe phenotypes of chronic inflammation, including allergic inflammation …
Persistent regulatory T‐cell response 2 years after 3 years of grass tablet SLIT: Links to reduced eosinophil counts, sIgE levels, and clinical benefit
R Varona, T Ramos, MM Escribese, L Jimeno… - Allergy, 2019 - Wiley Online Library
Background In the first 2 years of grass tablet sublingual immunotherapy treatment, we have
previously demonstrated a progressive development of a regulatory T‐cell response, which …
previously demonstrated a progressive development of a regulatory T‐cell response, which …
Exploring novel systemic biomarker approaches in grass‐pollen sublingual immunotherapy using omics
TC Barker‐Tejeda, R Bazire, D Obeso… - Allergy, 2021 - Wiley Online Library
Background Sublingual allergen‐specific immunotherapy (SLIT) intervention improves the
control of grass pollen allergy by maintaining allergen tolerance after cessation. Despite its …
control of grass pollen allergy by maintaining allergen tolerance after cessation. Despite its …
A qualitative and quantitative comparison of IgE antibody profiles with two multiplex platforms for component‐resolved diagnostics in allergic patients
Background Clinically complex phenotypes require more and more sophisticated and
comprehensive diagnostic approaches, able to discriminate genuine sensitizations from …
comprehensive diagnostic approaches, able to discriminate genuine sensitizations from …
Celiac disease causes epithelial disruption and regulatory T cell recruitment in the oral mucosa
J Sanchez-Solares, L Sanchez… - Frontiers in …, 2021 - frontiersin.org
Celiac disease (CD) is a chronic autoimmune disease characterized by an immune-
triggered enteropathy upon gluten intake. The only current treatment available is lifelong …
triggered enteropathy upon gluten intake. The only current treatment available is lifelong …