IL-17 and IL-17-producing cells in protection versus pathology
KHG Mills - Nature Reviews Immunology, 2023 - nature.com
IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …
immunity against many pathogens but also driving inflammatory pathology during infection …
Cutaneous leishmaniasis: immune responses in protection and pathogenesis
Cutaneous leishmaniasis is a major public health problem and causes a range of diseases
from self-healing infections to chronic disfiguring disease. Currently, there is no vaccine for …
from self-healing infections to chronic disfiguring disease. Currently, there is no vaccine for …
Pro-and anti-inflammatory cytokines in cutaneous leishmaniasis: a review
Cutaneous leishmaniasis (CL) is caused by different species of the genus Leishmania. Pro-
and anti-inflammatory cytokines play different roles in resistance/susceptibility and the …
and anti-inflammatory cytokines play different roles in resistance/susceptibility and the …
Possibilities and challenges for developing a successful vaccine for leishmaniasis
Leishmaniasis is a vector-borne disease caused by different species of protozoan parasites
of the genus Leishmania. It is a major health problem yet neglected tropical diseases, with …
of the genus Leishmania. It is a major health problem yet neglected tropical diseases, with …
Biology of interleukin-17 and its pathophysiological significance in sepsis
Y Ge, M Huang, Y Yao - Frontiers in immunology, 2020 - frontiersin.org
The interleukin (IL)-17 family includes six structure-related cytokines (A–F). To date, majority
of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases …
of studies have focused on IL-17A. IL-17A plays a pivotal role in various infectious diseases …
The Role of Nitric Oxide and Reactive Oxygen Species in the Killing of Leishmania braziliensis by Monocytes from Patients with Cutaneous Leishmaniasis
PP Carneiro, J Conceição, M Macedo, V Magalhães… - PloS one, 2016 - journals.plos.org
Human cutaneous leishmaniasis (CL) caused by Leishmania braziliensis, presents an
exaggerated Th1 response that is associated with ulcer development. Macrophages are the …
exaggerated Th1 response that is associated with ulcer development. Macrophages are the …
Host immune responses to the itch mite, Sarcoptes scabiei, in humans
SA Bhat, KE Mounsey, X Liu, SF Walton - Parasites & vectors, 2017 - Springer
Scabies is a parasitic disease due to infestation of skin by the burrowing mite Sarcoptes
scabiei. Scabies is a major public health problem and endemic in resource poor …
scabiei. Scabies is a major public health problem and endemic in resource poor …
The equivocal role of Th17 cells and neutrophils on immunopathogenesis of leishmaniasis
SC Gonçalves-de-Albuquerque… - Frontiers in …, 2017 - frontiersin.org
Advances in the understanding of leishmaniasis progression indicate that cellular
interactions more complex than the Th1/Th2 paradigm define the course of infection. Th17 …
interactions more complex than the Th1/Th2 paradigm define the course of infection. Th17 …
Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis
Patients infected with Leishmania braziliensis develop chronic lesions that often fail to
respond to treatment with antiparasite drugs. To determine whether genes whose …
respond to treatment with antiparasite drugs. To determine whether genes whose …
The balancing act: Immunology of leishmaniosis
AJ Toepp, CA Petersen - Research in veterinary science, 2020 - Elsevier
Immune control of Leishmania infantum, the causative agent of most canine leishmaniosis
(CanL), requires a balancing act between inflammatory and regulatory responses. This …
(CanL), requires a balancing act between inflammatory and regulatory responses. This …