Bacteria in cancer initiation, promotion and progression

G El Tekle, WS Garrett - Nature Reviews Cancer, 2023 - nature.com
Cancer cells originate from a series of acquired genetic mutations that can drive their
uncontrolled cell proliferation and immune evasion. Environmental factors, including the …

Examining horizontal gene transfer in microbial communities

IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Commensal microbiota from patients with inflammatory bowel disease produce genotoxic metabolites

Y Cao, J Oh, M Xue, WJ Huh, J Wang… - Science, 2022 - science.org
Microbiota-derived metabolites that elicit DNA damage can contribute to colorectal cancer
(CRC). However, the full spectrum of genotoxic chemicals produced by indigenous gut …

Role of the gut microbiota in anticancer therapy: from molecular mechanisms to clinical applications

LY Zhao, JX Mei, G Yu, L Lei, WH Zhang… - … and Targeted Therapy, 2023 - nature.com
In the past period, due to the rapid development of next-generation sequencing technology,
accumulating evidence has clarified the complex role of the human microbiota in the …

American gut: an open platform for citizen science microbiome research

D McDonald, E Hyde, JW Debelius, JT Morton… - Msystems, 2018 - Am Soc Microbiol
Although much work has linked the human microbiome to specific phenotypes and lifestyle
variables, data from different projects have been challenging to integrate and the extent of …

Genomics and pathotypes of the many faces of Escherichia coli

J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …

The role of the microbiome in cancer development and therapy

AP Bhatt, MR Redinbo… - CA: a cancer journal for …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE The human body harbors enormous numbers of
microbiota that influence cancer susceptibility, in part through their prodigious metabolic …

Unexpected guests in the tumor microenvironment: microbiome in cancer

A Wong-Rolle, HK Wei, C Zhao, C Jin - Protein & cell, 2021 - academic.oup.com
Although intestinal microbiome have been established as an important biomarker and
regulator of cancer development and therapeutic response, less is known about the role of …

Microbiome-wide association studies link dynamic microbial consortia to disease

JA Gilbert, RA Quinn, J Debelius, ZZ Xu, J Morton… - Nature, 2016 - nature.com
Rapid advances in DNA sequencing, metabolomics, proteomics and computational tools are
dramatically increasing access to the microbiome and identification of its links with disease …

[HTML][HTML] Gut microbiota imbalance and colorectal cancer

J Gagnière, J Raisch, J Veziant, N Barnich… - World journal of …, 2016 - ncbi.nlm.nih.gov
The gut microbiota acts as a real organ. The symbiotic interactions between resident micro-
organisms and the digestive tract highly contribute to maintain the gut homeostasis …