A multiscale framework for modeling fibrin fiber networks: Theory development and validation

N Filla, J Hou, H Li, X Wang - Journal of the Mechanics and Physics of …, 2023 - Elsevier
Fibrin fibers and fibrin network, the key structural components of blood clots, are imperative
for maintaining the functionality of blood clots in hemostasis and wound healing. Although …

Clots reveal anomalous elastic behavior of fiber networks

A Zakharov, M Awan, A Gopinath, SJJ Lee… - Science …, 2024 - science.org
The adaptive mechanical properties of soft and fibrous biological materials are relevant to
their functionality. The emergence of the macroscopic response of these materials to …

Analysis of fibrin networks using topological data analysis–a feasibility study

M Berger, T Hell, A Tobiasch, J Martini, A Lindner… - Scientific Reports, 2024 - nature.com
Blood clot formation, a crucial process in hemostasis and thrombosis, has garnered
substantial attention for its implications in various medical conditions. Microscopic …

Hyperelasticity of Blood Clots: Bridging the Gap between Microscopic and Continuum Scales

N Filla, B Gu, J Hou, K Song, H Li, N Liu… - Journal of the Mechanics …, 2024 - Elsevier
The biomechanical properties of blood clots, which are dictated by their compositions and
micro-structures, play a critical role in determining their fates, ie, occlusion, persistency, or …

Physically Based Modeling of Biological Semi-flexible Materials: A Novel Micromechanical Model Describing the Viscoelastic-Plastic Response of Agarose and Fibrin …

V Crespo-Cuevas - 2023 - search.proquest.com
In this Ph. D. thesis, I investigated the mechanics of soft matter, specifically focusing on the
viscoelastic-plastic response of agarose and fibrin networks. The study utilized a …

Hyperelasticity of Fibrin and Blood Clots

N Winter - 2023 - search.proquest.com
This dissertation aimed to provide an accurate, mechanistic, material model for blood clots,
thereby enabling the numerical study of blood clot pathologies and surgical intervention for …