Diabetic cardiomyopathy: an update of mechanisms contributing to this clinical entity

G Jia, MA Hill, JR Sowers - Circulation research, 2018 - Am Heart Assoc
Heart failure and related morbidity and mortality are increasing at an alarming rate, in large
part, because of increases in aging, obesity, and diabetes mellitus. The clinical outcomes …

[HTML][HTML] Diabetic cardiomyopathy: a hyperglycaemia-and insulin-resistance-induced heart disease

G Jia, A Whaley-Connell, JR Sowers - Diabetologia, 2018 - Springer
Diabetic cardiomyopathy is characterised in its early stages by diastolic relaxation
abnormalities and later by clinical heart failure in the absence of dyslipidaemia …

Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy

G Jia, VG DeMarco, JR Sowers - Nature Reviews Endocrinology, 2016 - nature.com
Insulin resistance, type 2 diabetes mellitus and associated hyperinsulinaemia can promote
the development of a specific form of cardiomyopathy that is independent of coronary artery …

[HTML][HTML] The role of epicardial adipose tissue in the development of atrial fibrillation, coronary artery disease and chronic heart failure in the context of obesity and type …

A Krishnan, H Sharma, D Yuan, AF Trollope… - Journal of …, 2022 - mdpi.com
Cardiovascular diseases (CVDs) are a significant burden globally and are especially
prevalent in obese and/or diabetic populations. Epicardial adipose tissue (EAT) surrounding …

Current understanding of structural and molecular changes in diabetic cardiomyopathy

MS Akhtar, SS Alavudeen, A Raza, MT Imam… - Life Sciences, 2023 - Elsevier
Diabetic Mellitus has been characterized as the most prevalent disease throughout the
globe associated with the serious morbidity and mortality of vital organs. Cardiomyopathy is …

The increasing detection of asymptomatic left ventricular dysfunction in patients with type 2 diabetes mellitus without overt cardiac disease: data from the …

G Faden, G Faganello, S De Feo, N Berlinghieri… - Diabetes research and …, 2013 - Elsevier
Aims Type 2 diabetes mellitus (DM) is associated with higher risk of heart failure. Over the
last three decades several studies demonstrated the presence of asymptomatic systolic …

[HTML][HTML] Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy

D Gong, S Sun, R Wang, A Dawuti, D Kong… - Biomedicine & …, 2023 - Elsevier
Salvianolic acid A (SAA) is a traditional Chinese medicine that has a good therapeutic effect
on cardiovascular disease. However, the underlying mechanisms by which SAA improves …

The relationships between cardiovascular disease and diabetes: focus on pathogenesis

JC Kovacic, JM Castellano… - Endocrinology and …, 2014 - endo.theclinics.com
The Relationships Between Cardiovascular Disease and Diabetes - Endocrinology and
Metabolism Clinics Skip to Main Content Skip to Main Menu Advertisement Endocrinology …

Diabetic cardiomyopathy: a clinical entity or a cluster of molecular heart changes?

M Mizamtsidi, SA Paschou, J Grapsa… - European journal of …, 2016 - Wiley Online Library
Background Although the increasing rate of cardiovascular mortality in patients with
diabetes is thought to be due to the coronary atherosclerosis caused mainly by …

[HTML][HTML] Effects of bergamot polyphenols on mitochondrial dysfunction and sarcoplasmic reticulum stress in diabetic cardiomyopathy

J Maiuolo, C Carresi, M Gliozzi, V Musolino, F Scarano… - Nutrients, 2021 - mdpi.com
Cardiovascular disease is the leading cause of death and disability in the Western world. In
order to safeguard the structure and the functionality of the myocardium, it is extremely …