Improved understanding of the pathogenesis of atopic dermatitis in dogs has led to more
effective treatment plans, including skin barrier repair and new targeted treatments for …

The body's immune system is essential for protecting it from various pathogens and other
external insults. The immune system is tightly regulated and maintained through the …

Cyclosporine is an immunomodulatory drug used to treat an increasing spectrum of
diseases in dogs. Cyclosporine is a calcineurin inhibitor, ultimately exerting its inhibitory …

The body's immune system is essential for protecting it from a variety of pathogens and other
external insults. It is through the complex interactions between the cells and mediators of …

Ciclosporin (Atopica; Novartis Animal Health) has been licensed for canine atopic dermatitis
(AD) since 2002. Adverse events (AEs) have been reported in 55 per cent of 759 dogs in 15 …

Background Oclacitinib is a Janus kinase inhibitor used to control pruritus and skin lesions
in canine allergic skin disease; its effect on canine T cells is not well‐characterized …

Sixteen cats with chronic stomatitis, that had previously undergone premolar-molar or full-
mouth extractions, were randomly assigned a group to receive 2.5 mg/kg cyclosporine or …

Clinical Immunology of the Dog and Cat Page 1 Page 2 CLINICAL IMMUNOLOGY OF THE DOG
AND CAT Second Edition Revised And Updated Michael J Day BSc BVMS (Hons) PhD DSc …

Cyclosporine A (CsA) is an immunomodulatory medication that was initially isolated from the
fungus Tolypocladium inflatum. 1 It has been successfully used in the treatment of a variety …

Background Pharmacodynamic assays measure the immunosuppressive effects of
cyclosporine on T‐cells and offer an alternative assessment of efficacy in individual patients …