Heart blood flow simulation: a perspective review

SN Doost, D Ghista, B Su, L Zhong… - Biomedical engineering …, 2016 - Springer
Cardiovascular disease (CVD), the leading cause of death today, incorporates a wide range
of cardiovascular system malfunctions that affect heart functionality. It is believed that the …

Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities

L Zhong, JM Zhang, B Su, RS Tan, JC Allen… - Frontiers in …, 2018 - frontiersin.org
The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to
the challenging field of virtual design and testing of technologies in a patient-specific …

An image-based computational fluid dynamics study of mitral regurgitation in presence of prolapse

L Bennati, C Vergara, V Giambruno, I Fumagalli… - Cardiovascular …, 2023 - Springer
Purpose In this work we performed an imaged-based computational study of the systolic
fluid dynamics in presence of mitral valve regurgitation (MVR). In particular, we compared …

Turbulent blood dynamics in the left heart in the presence of mitral regurgitation: a computational study based on multi-series cine-MRI

L Bennati, V Giambruno, F Renzi, V Di Nicola… - … and Modeling in …, 2023 - Springer
In this work, we performed a computational image-based study of blood dynamics in the
whole left heart, both in a healthy subject and in a patient with mitral valve regurgitation. We …

Personalized intervention cardiology with transcatheter aortic valve replacement made possible with a non-invasive monitoring and diagnostic framework

S Khodaei, A Henstock, R Sadeghi, S Sellers… - Scientific reports, 2021 - nature.com
One of the most common acute and chronic cardiovascular disease conditions is aortic
stenosis, a disease in which the aortic valve is damaged and can no longer function …

[HTML][HTML] Polytopal discontinuous Galerkin discretization of brain multiphysics flow dynamics

I Fumagalli, M Corti, N Parolini, PF Antonietti - Journal of Computational …, 2024 - Elsevier
A comprehensive mathematical model of the multiphysics flow of blood and Cerebrospinal
Fluid (CSF) in the brain can be expressed as the coupling of a poromechanics system and …

An Eulerian finite element method for PDEs in time-dependent domains

C Lehrenfeld, M Olshanskii - ESAIM: Mathematical Modelling and …, 2019 - esaim-m2an.org
The paper introduces a new finite element numerical method for the solution of partial
differential equations on evolving domains. The approach uses a completely Eulerian …

CT-based analysis of left ventricular hemodynamics using statistical shape modeling and computational fluid dynamics

L Goubergrits, K Vellguth, L Obermeier… - Frontiers in …, 2022 - frontiersin.org
Background Cardiac computed tomography (CCT) based computational fluid dynamics
(CFD) allows to assess intracardiac flow features, which are hypothesized as an early …

Towards a non-invasive computational diagnostic framework for personalized cardiology of transcatheter aortic valve replacement in interactions with complex …

S Khodaei, R Sadeghi, P Blanke, J Leipsic… - International Journal of …, 2021 - Elsevier
Aortic stenosis is an acute and chronic cardiovascular disease that often coexists with other
complex valvular, ventricular and vascular diseases (C3VD). Transcatheter aortic valve …

[HTML][HTML] Numerical simulations of flow patterns in the human left ventricle model with a novel dynamic mesh morphing approach based on radial basis function

F Xu, S Kenjereš - Computers in Biology and Medicine, 2021 - Elsevier
We present a new numerical simulation framework for prediction of flow patterns in the
human left ventricle model. In this study, a radial basis function (RBF) mesh morphing …