COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

Nanostructured particles assembled from natural building blocks for advanced therapies

Y Ju, H Liao, JJ Richardson, J Guo… - Chemical Society …, 2022 - pubs.rsc.org
Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …

Effect of mRNA vaccine boosters against SARS-CoV-2 Omicron infection in Qatar

LJ Abu-Raddad, H Chemaitelly… - … England Journal of …, 2022 - Mass Medical Soc
Background Waning of vaccine protection against coronavirus disease 2019 (Covid-19) and
the emergence of the omicron (or B. 1.1. 529) variant of the severe acute respiratory …

A ferritin-based COVID-19 nanoparticle vaccine that elicits robust, durable, broad-spectrum neutralizing antisera in non-human primates

PAB Weidenbacher, M Sanyal, N Friedland… - Nature …, 2023 - nature.com
While the rapid development of COVID-19 vaccines has been a scientific triumph, the need
remains for a globally available vaccine that provides longer-lasting immunity against …

Challenges and developments in universal vaccine design against SARS-CoV-2 variants

F Zhao, X Zai, Z Zhang, J Xu, W Chen - npj Vaccines, 2022 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had
become a global concern because of its unexpectedly high pathogenicity and …

[HTML][HTML] Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease

P Zhou, G Song, H Liu, M Yuan, W He, N Beutler, X Zhu… - Immunity, 2023 - cell.com
Pan-betacoronavirus neutralizing antibodies may hold the key to developing broadly
protective vaccines against novel pandemic coronaviruses and to more effectively respond …

Adjuvant physiochemistry and advanced nanotechnology for vaccine development

H Ren, W Jia, Y Xie, M Yu, Y Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Vaccines comprising innovative adjuvants are rapidly reaching advanced translational
stages, such as the authorized nanotechnology adjuvants in mRNA vaccines against COVID …

Shark nanobodies with potent SARS-CoV-2 neutralizing activity and broad sarbecovirus reactivity

WH Chen, A Hajduczki, EJ Martinez, H Bai… - Nature …, 2023 - nature.com
Despite rapid and ongoing vaccine and therapeutic development, SARS-CoV-2 continues to
evolve and evade, presenting a need for next-generation diverse therapeutic modalities …

Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses

W He, R Musharrafieh, G Song, K Dueker, LV Tse… - Nature …, 2022 - nature.com
The emergence of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants of concern (VOCs) and potential future spillovers of SARS-like coronaviruses into …

Engineering nanomaterial physical characteristics for cancer immunotherapy

DY Lee, K Huntoon, J Lux, BYS Kim… - Nature Reviews …, 2023 - nature.com
The physical properties of nanomaterials—such as size, structure, shape, charge,
mechanical strength and hydrophobicity—can directly or indirectly influence immune cell …