Podophyllum hexandrum fraction (REC-2006) shows higher radioprotective efficacy in the p53-carrying hepatoma cell line: a role of cell cycle regulatory proteins

PK Singh, R Kumar, A Sharma… - Integrative Cancer …, 2009 - journals.sagepub.com
The present study was carried out to evaluate the radioprotective efficacy of Podophyllum
hexandrum fraction (REC-2006) in hepatoma cell lines having different p53 statuses. Higher …

[PDF][PDF] Radioprotective activities of Podophyllum hexandrum: current knowledge of the molecular mechanisms

R Kumar, PK Singh, R Arora, R Chawla… - Trees for life …, 2009 - academia.edu
Radiation is one of the most severe causes of oxidative stress mediated by free radical flux.
This flux interferes with oxidation/reduction-based physiological mechanisms existing inside …

Pifithrin‐α decreases the radioprotective efficacy of a Podophyllum hexandrum (Himalayan mayapple) fraction (REC‐2006) in HepG2 cells

PK Singh, R Kumar, A Sharma, R Arora… - Biotechnology and …, 2009 - Wiley Online Library
Inhibition of the tumour suppressor p53 by PFT (pifithrin‐α) promotes p53‐mediated
apoptosis and protects against doxorubicin‐induced apoptosis. The present study was …

Role of Apoptotic Proteins in REC‐2006 Mediated Radiation Protection in Hepatoma Cell Lines

PK Singh, R Kumar, A Sharma, R Arora… - Evidence‐Based …, 2011 - Wiley Online Library
The present study was carried out to evaluate the role of apoptotic proteins in REC‐2006‐
mediated radiation protection in hepatoma cell lines. REC‐2006 treatment 2 h before …