Idiopathic pulmonary fibrosis (IPF) is a restrictive lung disease that is associated with high
morbidity and mortality. Current medical therapies are not fully effective at limiting mortality …

Sixteen years ago, the Nomenclature Committee of the International Union of Pharmacology
approved a system for naming human seven-transmembrane (7TM) G protein-coupled …

Burns and other traumatic injuries represent a substantial biomedical burden. The current
standard of care for deep injuries is autologous split-thickness skin grafting (STSG), which …

CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …

CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …

Pulmonary fibrosis (PF) is characterized by aberrant extracellular matrix (ECM) deposition,
activation of fibroblasts to myofibroblasts and parenchymal disorganization, which have an …

Pulmonary fibrosis occurs in a variety of clinical settings, constitutes a major cause of
morbidity and mortality, and represents an enormous unmet medical need. However, the …

Different animal models of pulmonary fibrosis have been developed to investigate potential
therapies for idiopathic pulmonary fibrosis (IPF). The most common is the bleomycin model …

Aberrant wound-healing responses to injury have been implicated in the development of
pulmonary fibrosis, but the mediators directing these pathologic responses have yet to be …

Myocardial infarction is the most common cause of cardiac injury and results in acute loss of
a large number of myocardial cells. Because the heart has negligible regenerative capacity …