Current developments of coumarin compounds in medicinal chemistry

XM Peng, G LV Damu, H Zhou - Current pharmaceutical …, 2013 - ingentaconnect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Biologically active quinoline and quinazoline alkaloids part II

XF Shang, SL Morris‐Natschke… - Medicinal research …, 2018 - Wiley Online Library
To follow‐up on our prior Part I review, this Part II review summarizes and provides updated
literature on novel quinoline and quinazoline alkaloids isolated during the period of 2009 …

Natural product based leads to fight against leishmaniasis

N Singh, BB Mishra, S Bajpai, RK Singh… - Bioorganic & medicinal …, 2014 - Elsevier
The growing incidence of parasitic resistance against generic pentavalent antimonials,
specifically for visceral disease in Indian subcontinent, is a serious issue in Leishmania …

Natural and synthetic coumarins as antileishmanial agents: A review

GA Gonçalves, AR Spillere, GM das Neves… - European Journal of …, 2020 - Elsevier
The neglected tropical disease leishmaniasis is still a major public health problem that
affects millions of people worldwide. Related to poor-living conditions, this vector-borne …

[HTML][HTML] Use of natural products in leishmaniasis chemotherapy: an overview

LFO Gervazoni, GB Barcellos, T Ferreira-Paes… - Frontiers in …, 2020 - frontiersin.org
Leishmaniasis is an infectious parasitic disease that is caused by protozoa of the genus
Leishmania, a member of the Trypanosomatidae family. Leishmaniasis is classified by the …

Antileishmanial drug discovery: Comprehensive review of the last 10 years

JN Sangshetti, FAK Khan, AA Kulkarni, R Arote… - Rsc Advances, 2015 - pubs.rsc.org
Leishmaniasis, a group of diseases caused by hemoflagellate obligate intracellular protozoa
(trypanosomatids) from the genus Leishmania, has not received the attention it deserves …

Plant derived therapeutics for the treatment of Leishmaniasis

R Sen, M Chatterjee - Phytomedicine, 2011 - Elsevier
Diseases caused by insect borne trypanosomatid parasites are significant, yet remain a
neglected public health problem. Leishmania, a unicellular protozoan parasite is the …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

Leishmania treatment and prevention: Natural and synthesized drugs

AA Bekhit, E El-Agroudy, A Helmy, TM Ibrahim… - European journal of …, 2018 - Elsevier
Leishmaniasis affects over 150 million people all over the world, especially in subtropical
regions. Currently used antileishmanial synthesized drugs are associated with some …