Detergent-free isolation of membrane proteins and strategies to study them in a near-native membrane environment

B Krishnarjuna, A Ramamoorthy - Biomolecules, 2022 - mdpi.com
Atomic-resolution structural studies of membrane-associated proteins and peptides in a
membrane environment are important to fully understand their biological function and the …

Microfluidic formulation of anticancer peptide loaded ZIF-8 nanoparticles for the treatment of breast cancer

J Qiu, MA Tomeh, Y Jin, B Zhang, X Zhao - Journal of Colloid and Interface …, 2023 - Elsevier
Anticancer peptides (ACPs) are promising antitumor drugs owning to their great cancer cell
targeting and anticancer effects as well as low drug resistance. However, many of the ACPs …

Chemistry and Functions of Imported Fire Ant Venom

J Chen - Toxins, 2023 - mdpi.com
In the United States, imported fire ants are often referred to as red imported fire ants,
Solenopsis invicta Buren, black imported fire ants, S. richteri Forel, and their hybrid (S …

Characterization of nanodisc-forming peptides for membrane protein studies

B Krishnarjuna, G Sharma, SC Im, R Auchus… - Journal of Colloid and …, 2024 - Elsevier
Lipid-bilayer nanodiscs provide a stable, native-like membrane environment for the
functional and structural studies of membrane proteins and other membrane-binding …

[HTML][HTML] Profiling hymenopteran venom toxins: Protein families, structural landscape, biological activities, and pharmacological benefits

JC Guido-Patiño, F Plisson - Toxicon: X, 2022 - Elsevier
Hymenopterans are an untapped source of venom secretions. Their recent proteo-
transcriptomic studies have revealed an extraordinary pool of toxins that participate in …

Venomics survey of six myrmicine ants provides insights into the molecular and structural diversity of their peptide toxins

V Barassé, N Téné, C Klopp, F Paquet… - Insect Biochemistry and …, 2022 - Elsevier
Among ants, Myrmicinae represents the most speciose subfamily. The venom composition
previously described for these social insects is extremely variable, with alkaloids …

Multiomic Approach for Bioprospection: Investigation of Toxins and Peptides of Brazilian Sea Anemone Bunodosoma caissarum

ME Mazzi Esquinca, CN Correa, G Marques de Barros… - Marine Drugs, 2023 - mdpi.com
Sea anemones are sessile invertebrates of the phylum Cnidaria and their survival and
evolutive success are highly related to the ability to produce and quickly inoculate venom …

Using protein–metabolite interactions to identify novel plant metabolite receptors

HD Fischer, A Fernie, A Skirycz - Phytochemistry Reviews, 2024 - Springer
An increasing interest in plant protein–metabolite interactions has occurred in the past
decade due to advancements in technology and methodology. Metabolite receptors …

Fish-hunting cone snail disrupts prey's glucose homeostasis with weaponized mimetics of somatostatin and insulin

HY Yeung, IBL Ramiro, DB Andersen, TL Koch… - Nature …, 2024 - nature.com
Venomous animals have evolved diverse molecular mechanisms to incapacitate prey and
defend against predators. Most venom components disrupt nervous, locomotor, and …

Venom composition and pain-causing toxins of the Australian great carpenter bee Xylocopa aruana

N Shi, TG Szanto, J He, CI Schroeder, AA Walker… - Scientific Reports, 2022 - nature.com
Most species of bee are capable of delivering a defensive sting which is often painful. A
solitary lifestyle is the ancestral state of bees and most extant species are solitary, but …