Clostridioides difficile (formerly Clostridium difficile) infection is a substantial health and
economic burden worldwide. Great strides have been made over the past several years in …

Clostridioides difficile is an anaerobic Gram-positive and spore-forming bacterium. The
majority of C. difficile strains produce two toxins, A and B, associated with the development …

Clostridioides difficile is an obligate anaerobic pathogen among the most common causes of
healthcare-associated infections. It poses a global threat due to the clinical outcomes of …

We evaluated whether hospitalized patients without diagnosed Clostridioides difficile
infection (CDI) increased the risk for CDI among their family members after discharge. We …

Objective This study aimed to evaluate the fecal shedding of C. difficile in calves on farms in
Sao Paulo State, Brazil. Materials and methods Fecal samples (n= 300) were collected from …

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, leading
to fibrosis, cirrhosis and hepatocellular carcinoma and also associated with increased …

Background Antibiotic treatment is a well-known risk factor for Clostridioides difficile infection
(CDI). The time from start of antibiotic exposure to onset of CDI for different antibiotics is …

Clostridioides difficile infection (CDI) incidence has increased over the last 20 years. Studies
suggest that asymptomatic carriers may be an important reservoir of C. difficile in healthcare …

Objective: The days of therapy (DOT) metric, used to estimate antimicrobial consumption,
has some limitations. Days of antibiotic spectrum coverage (DASC), a novel metric …

Clostridioides difficile is a strictly anaerobic, spore-forming Gram-positive bacterium
associated with diarrhea, known as C. difficile infection (CDI). In domestic animals, C …