Tumor necrosis factor receptor–associated factor (TRAF) proteins are key signaling
molecules that function in various cellular signaling events including immune response, cell …

Purpose TRAF4 plays an important role in the development and progression of breast
cancer, but its impact on chemotherapy resistance is as yet, however, poorly understood …

Asparaginyl endopeptidase (AEP) is an endo/lysosomal cysteine endopeptidase with a
preference for an asparagine residue at the P1 site and plays an important role in the …

Normal fibroblasts surrounding tumor cells play a crucial role in cancer progression through
formation of the tumor microenvironment. Because factors secreted from normal fibroblasts …

TRAF7 serves as a crucial intracellular adaptor and E3 ubiquitin ligase involved in signal
transduction pathways, contributing to immune responses, tumor progression, and …

Several studies have been conducted over the years to unravel the structural information on
the receptors that bind to tumor necrosis factor receptor-associated factor (TRAF) and the …

Previously, we established that as a function of its mode of interaction with its ligand or
cellular conditions such as membrane lipids, preexisting signaling intermediates activation …

Tumor necrosis factor receptor‐associated factors (TRAFs) constitute a family of adapter
proteins that act in numerous signaling pathways important in human biology and disease …

NADPH oxidase (NOX)-derived reactive oxygen species (ROS) and copper (Cu), an
essential micronutrient, have been implicated in vascular inflammatory diseases. We …

The tumor necrosis factor (TNF) receptor associated factors (TRAFs) are the major signal
transducers for the TNF receptor superfamily and the interleukin-1 receptor/Toll-like receptor …