Mathematical models have a long history in epidemiological research, and as the COVID-19
pandemic progressed, research on mathematical modeling became imperative and very …

Dengue fever is caused by infection with one of four dengue virus (DENV) serotypes (DENV-
1–4), necessitating tetravalent dengue vaccines that can induce protection against all four …

Background: With its tropical rainforest climate, rapid urbanization, and changing
demography and ecology, Singapore experiences endemic dengue; the last large outbreak …

Dengue is considered non-endemic to mainland China. However, travellers frequently
import the virus from overseas and local mosquito species can then spread the disease in …

For the evaluation of infectious-diseases interventions, the transmissible nature of such
diseases plays a central role. Agent-based models (ABM) allow for dynamic transmission …

Background A tetravalent dengue vaccine was shown to be efficacious against symptomatic
dengue in two phase III efficacy studies performed in five Asian and five Latin American …

Background A tetravalent dengue vaccine demonstrated its protective efficacy in two phase
III efficacy studies. Results from these studies were used to derive vaccination impact in the …

Background The escalation of dengue fever (DF) cases in recent years and the occurrence
of a large-scale DF outbreak in 2017 underline the importance of dengue vaccines in …

The prevention and control of dengue are great public health challenges for many countries,
particularly since 2015, as other arboviruses have been observed to interact significantly …

The only rubella vaccine available in North America is the RA27/3 strain (isolated from the
kidney of a rubella-infected fetus and attenuated) licensed in 1979, which substituted …