MicroRNA (miRNA) is a non-coding single-stranded small molecule of approximately 21
nucleotides. It degrades or inhibits the translation of RNA by targeting the 3′-UTR. The …

Huntington's disease (HD) is an extraordinary disorder that usually strikes when individuals
are in the prime of their lives, as was the case for the influential 20th century musician …

Huntington's disease (HD) is a lethal neurodegenerative disorder without efficient
therapeutic options. The inefficient translation from preclinical and clinical research into …

While Huntington disease (HD) is caused solely by a polyglutamine expansion in the
huntingtin gene, environmental factors can influence HD onset and progression. Here, we …

Huntington's disease (HD) is a rare, incurable, inherited neurodegenerative disorder
manifested by chorea, hyperkinetic, and hypokinetic movements. The FDA has approved …

A neurodegenerative disorder (ND) refers to Huntington's disease (HD) which affects
memory loss, weight loss, and movement dysfunctions such as chorea and dystonia. In the …

Depression is a common psychiatric disorder among individuals with Huntington's disease
(HD). Depression in HD and major depressive disorder appear to have different …

Huntington's disease (HD) is an autosomal dominant progressive brain disorder, caused by
a pathological expansion of a CAG repeat that encodes the huntingtin gene. This genetic …

Apathy is pervasive across many neuropsychiatric disorders but is poorly characterized
mechanistically, so targeted therapeutic interventions remain elusive. A key impediment has …

Huntington Disease (HD) is an incurable autosomal dominant single gene
neurodegenerative disorder. Typical onset is between 30 and 40 years and characterised by …