New pathogens, new tricks: emerging, drug‐resistant fungal pathogens and future prospects for antifungal therapeutics
J Geddes‐McAlister, RS Shapiro - … of the New York Academy of …, 2019 - Wiley Online Library
Fungal pathogens are a growing threat to public health. As human immunodeficiency
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
becomes increasingly common, fungal infections are becoming more prevalent. The use of …
Novel strategies to combat the emerging drug resistance in human pathogenic microbes
The major health-care burden for the developing world are infectious diseases where
antimicrobial agents prove to be the magical drugs to combat this. But the phenomenon of …
antimicrobial agents prove to be the magical drugs to combat this. But the phenomenon of …
[HTML][HTML] Innate inspiration: antifungal peptides and other immunotherapeutics from the host immune response
DK Mercer, DA O'Neil - Frontiers in Immunology, 2020 - frontiersin.org
The purpose of this review is to describe antifungal therapeutic candidates in preclinical and
clinical development derived from, or directly influenced by, the immune system, with a …
clinical development derived from, or directly influenced by, the immune system, with a …
[HTML][HTML] Fungal vaccine development: State of the art and perspectives using Immunoinformatics
MM Inácio, ALE Moreira, VRM Cruz-Leite, K Mattos… - Journal of Fungi, 2023 - mdpi.com
Fungal infections represent a serious global health problem, causing damage to health and
the economy on the scale of millions. Although vaccines are the most effective therapeutic …
the economy on the scale of millions. Although vaccines are the most effective therapeutic …
The mitochondrial complex I proteins of Candida albicans moderate phagocytosis and the production of pro‐inflammatory cytokines in murine macrophages and …
X She, P Zhang, D Shi, J Peng, Q Wang… - The FASEB …, 2022 - Wiley Online Library
Loss of respiratory functions impairs Candida albicans colonization of host tissues and
virulence in a murine model of candidiasis. Furthermore, it is known that respiratory …
virulence in a murine model of candidiasis. Furthermore, it is known that respiratory …
[HTML][HTML] Reinforcing the immunocompromised host defense against fungi: progress beyond the current state of the art
G Karavalakis, E Yannaki, A Papadopoulou - Journal of Fungi, 2021 - mdpi.com
Despite the availability of a variety of antifungal drugs, opportunistic fungal infections still
remain life-threatening for immunocompromised patients, such as those undergoing …
remain life-threatening for immunocompromised patients, such as those undergoing …
Usefulness of animal models of aspergillosis in studying immunity against Aspergillus infections
I Mirkov, AP Aleksandrov, B Lazovic… - Journal de Mycologie …, 2019 - Elsevier
Aspergillosis represents a spectrum of fungal diseases which are caused by fungi of the
genus Aspergillus. Animal models have been developed and used to address immune …
genus Aspergillus. Animal models have been developed and used to address immune …
Fungal Vaccine Development: State of the Art and Perspectives Using Immunoinformatics
O Hernández Ruiz, CM de Almeida Soares… - 2023 - bibliotecadigital.udea.edu.co
Fungal infections represent a serious global health problem, causing damage to health and
the economy on the scale of millions. Although vaccines are the most effective therapeutic …
the economy on the scale of millions. Although vaccines are the most effective therapeutic …