In the developing embryo, tissues differentiate, deform, and move in an orchestrated manner
to generate various biological shapes driven by the complex interplay between genetic …

Mechanotransduction translates mechanical signals into biochemical signals. It is based on
the soft-matter properties of biomolecules or membranes that deform in response to …

It is becoming increasingly clear that cells are remarkably sensitive to the biophysical cues
of their microenvironment and that these cues play a significant role in influencing their …

The heart is the first functioning organ to form during development. During gastrulation, the
cardiac progenitors reside in the lateral plate mesoderm but maintain close contact with the …

The fundamental physical features such as the mechanical properties and microstructures of
the uterus need to be considered when building in vitro culture platforms to mimic the uterus …

In the last four decades, the assisted reproductive technology (ART) field has witnessed
advances, resulting in improving pregnancy rates and diminishing complications, in …

A couple of decades ago, when I first heard the term mechanobiology, I thought it was just a
fancy and more modern name for biomechanics. While there certainly is overlap between …

In the early embryo, the primitive heart tube (HT) undergoes the morphogenetic process of c-
looping as it bends and twists into a c-shaped tube. Despite intensive study for nearly a …

The morphogenetic process of cardiac looping transforms the straight heart tube into a
curved tube that resembles the shape of the future four-chambered heart. Although great …

During early vertebrate development, local constrictions, or sulci, form to divide the forebrain
into the diencephalon, telencephalon, and optic vesicles. These partitions are maintained …