Mitochondrial dysfunction and oxidative stress caused by cryopreservation in reproductive cells

R Gualtieri, G Kalthur, V Barbato, M Di Nardo, SK Adiga… - Antioxidants, 2021 - mdpi.com
Mitochondria, fundamental organelles in cell metabolism, and ATP synthesis are
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …

Sperm oxidative stress during in vitro manipulation and its effects on sperm function and embryo development

R Gualtieri, G Kalthur, V Barbato, S Longobardi… - Antioxidants, 2021 - mdpi.com
Reactive oxygen species (ROS) generated at low levels during mitochondrial respiration
have key roles in several signaling pathways. Oxidative stress (OS) arises when the …

Chang's meaning of capacitation: A molecular perspective

MG Gervasi, PE Visconti - Molecular Reproduction and …, 2016 - Wiley Online Library
SUMMARY Dr. Min Chue Chang's contributions to the field of reproductive biology set the
stage for the development of the contraceptive pill and in vitro fertilization. Throughout his …

Reactive oxygen species and protein modifications in spermatozoa

C O'Flaherty, D Matsushita-Fournier - Biology of Reproduction, 2017 - academic.oup.com
Cellular response to reactive oxygen species (ROS) includes both reversible redox
signaling and irreversible nonenzymatic reactions which depend on the nature and …

Redox regulation and oxidative stress: The particular case of the stallion spermatozoa

FJ Peña, C O'Flaherty, JM Ortiz Rodríguez… - Antioxidants, 2019 - mdpi.com
Redox regulation and oxidative stress have become areas of major interest in spermatology.
Alteration of redox homeostasis is recognized as a significant cause of male factor infertility …

Oocyte developmental failure in response to elevated nonesterified fatty acid concentrations: mechanistic insights

V Van Hoeck, J Leroy, MA Alvarez, D Rizos… - …, 2013 - rep.bioscientifica.com
The aim of this study was to evaluate the distribution of inhibin/activin alpha, beta (A) and
beta (B) subunits and follistatin in immature oocytes and in matured oocytes before and after …

Molecules involved in sperm-oviduct adhesion and release

R Talevi, R Gualtieri - Theriogenology, 2010 - Elsevier
In mammals, sperm ascension within the female reproductive tract involves a transient
adhesion to the caudal isthmus of the oviduct. Sperm adhesion to this specialized region …

The oviduct as a complex mediator of mammalian sperm function and selection

WV Holt, A Fazeli - Molecular reproduction and development, 2010 - Wiley Online Library
The fallopian tube, or oviduct, is no longer considered merely a conduit that joins the uterine
horns and the ovaries, being recognised as a venue for the capacitation of spermatozoa and …

Sperm selection in the female mammalian reproductive tract. Focus on the oviduct: hypotheses, mechanisms, and new opportunities

WV Holt, A Fazeli - Theriogenology, 2016 - Elsevier
Research over the past 3 decades has caused a major shift in the way that the oviduct, or
fallopian tube, is perceived. Previously, it was regarded as little more than the anatomic site …

Oviductal secretion and gamete interaction

S Ghersevich, E Massa, C Zumoffen - Reproduction, 2015 - rep.bioscientifica.com
A reliable, easy to assess marker for fertility in agricultural species would be highly desirable
and Anti-Müllerian Hormone (AMH) is a promising candidate. This review summarizes …